Cdkn1a Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:324706 Lu J, et al., Znhit1 Regulates p21Cip1 to Control Mouse Lens Differentiation. Invest Ophthalmol Vis Sci. 2022 Apr 1;63(4):18
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7328644
Gene symbol:	Cdkn1a
Gene name:	cyclin dependent kinase inhibitor 1A

Antibody:	anti-p21Cip1 [EPR18021] (ab188224)
Detection system:	Secondary antibody coupled to Alexa Fluor 555

Results

8G ©

8G' ©

8G'' ©

Specimen 8G,G',G'': postnatal day 0.5; Znhit1^tm1.1Nju/Znhit1^tm1.1Nju (more

)

Structure	Level	Pattern	Image	Note
TS27: lens	Absent		8G'' , 8G' , 8G	Expression repressed; not detected in control mice.

8H ©

8H' ©

8H'' ©

Specimen 8H,H',H'': postnatal day 0.5; Tg(Cryaa-cre)10Mlr/0, Znhit1^tm1.1Nju/Znhit1^tm1.1Nju (more

)
Note: Conditional mutant.

Structure	Cell Type	Level	Pattern	Image	Note
TS27: lens	lens fiber cell	Strong	Regionally restricted	8H' , 8H'' , 8H	Ectopic expression in nuclei of differentiated lens fiber cells.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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