Cdkn1b Immunohistochemistry Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:324706 Lu J, et al., Znhit1 Regulates p21Cip1 to Control Mouse Lens Differentiation. Invest Ophthalmol Vis Sci. 2022 Apr 1;63(4):18
Assay type:	Immunohistochemistry
MGI Accession ID:	MGI:7328642
Gene symbol:	Cdkn1b
Gene name:	cyclin dependent kinase inhibitor 1B

Antibody:	anti-p27Kip1 [SX53G8] (ab193379)
Detection system:	Secondary antibody coupled to Alexa Fluor 488

Results

8A ©

8A' ©

Specimen 8A,A': postnatal day 0.5; Znhit1^tm1.1Nju/Znhit1^tm1.1Nju (more

)

Structure	Cell Type	Level	Pattern	Image	Note
TS27: lens fiber	lens fiber cell	Present	Regionally restricted	8A , 8A'	Expression in lens fiber cells at lens equator transitional zone.

8B ©

8B' ©

Specimen 8B,B': postnatal day 0.5; Tg(Cryaa-cre)10Mlr/0, Znhit1^tm1.1Nju/Znhit1^tm1.1Nju (more

)
Note: Conditional mutant.

Structure	Cell Type	Level	Pattern	Image	Note
TS27: lens fiber	lens fiber cell	Present	Regionally restricted	8B' , 8B	Expression similar to control in cells localized in lens equatorial region.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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