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Gene Expression Data
Assay Details
Assay
Reference: J:324706 Lu J, et al., Znhit1 Regulates p21Cip1 to Control Mouse Lens Differentiation. Invest Ophthalmol Vis Sci. 2022 Apr 1;63(4):18
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7328637
Gene symbol: Znhit1
Gene name: zinc finger, HIT domain containing 1
Antibody: anti-Znhit1 (HAP019043)
Detection system: Secondary antibody coupled to Alexa Fluor 555
Results
Specimen 1C,C': embryonic day 13.5 (more )
Structure Cell Type Level Pattern Image Note
TS21: lens epithelium lens epithelial cell Strong 1C , 1C'
TS21: lens fiber lens fiber cell Strong 1C , 1C'
Specimen 1D,D': postnatal day 0.5 (more )
Structure Cell Type Level Pattern Image Note
TS27: lens epithelium lens epithelial cell Strong 1D' , 1D
TS27: lens fiber lens fiber cell Strong 1D , 1D'
Specimen 1E,E': postnatal day 7 (more )
Structure Cell Type Level Pattern Image Note
TS28: lens epithelium lens epithelial cell Weak 1E , 1E'
TS28: lens fiber lens fiber cell Weak 1E , 1E'
Specimen 1F,F': postnatal week 3 (more )
Structure Cell Type Level Pattern Image Note
TS28: lens epithelium lens epithelial cell Trace 1F' , 1F
TS28: lens fiber lens fiber cell Trace 1F , 1F'
Specimen 1G,G': postnatal week 12 (more )
Structure Cell Type Level Pattern Image Note
TS28: lens epithelium lens epithelial cell Trace 1G' , 1G
TS28: lens fiber lens fiber cell Trace 1G , 1G'
Specimen 2A,A': embryonic day 13.5; Znhit1tm1.1Nju/Znhit1tm1.1Nju (more )
Structure Cell Type Level Pattern Image Note
TS21: lens epithelium lens epithelial cell Strong 2A' , 2A
TS21: lens fiber lens fiber cell Strong 2A' , 2A
Specimen 2B,B': embryonic day 13.5; Tg(Cryaa-cre)10Mlr/0, Znhit1tm1.1Nju/Znhit1tm1.1Nju (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS21: lens epithelium lens epithelial cell Present 2B' , 2B Expression decreased in both lens epithelial cells and fiber cells at E13.5 and P0.5.
TS21: lens fiber lens fiber cell Present 2B , 2B' Expression decreased in both lens epithelial cells and fiber cells at E13.5 and P0.5.
Specimen 2C,C': postnatal day 0.5; Znhit1tm1.1Nju/Znhit1tm1.1Nju (more )
Structure Cell Type Level Pattern Image Note
TS27: lens epithelium lens epithelial cell Weak 2C' , 2C
TS27: lens fiber lens fiber cell Weak 2C , 2C'
Specimen 2D,D': postnatal day 0.5; Tg(Cryaa-cre)10Mlr/0, Znhit1tm1.1Nju/Znhit1tm1.1Nju (more )
Note: Conditional mutant.
Structure Cell Type Level Pattern Image Note
TS27: lens epithelium lens epithelial cell Trace 2D' , 2D Expression decreased in both lens epithelial cells and fiber cells at E13.5 and P0.5.
TS27: lens fiber lens fiber cell Trace 2D' , 2D Expression decreased in both lens epithelial cells and fiber cells at E13.5 and P0.5.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory