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Gene Expression Data
Assay Details
Assay
Reference: J:79855 Anderson RM, et al., Chordin and noggin promote organizing centers of forebrain development in the mouse. Development. 2002 Nov;129(21):4975-87
Assay type: RNA in situ
MGI Accession ID: MGI:7316497
Gene symbol: Fgf8
Gene name: fibroblast growth factor 8
Results
Specimen 4I: embryonic day 8.0 (more )
Note: 5 somites.
Structure Level Pattern Image Note
TS12: anterior neural ridge Present Regionally restricted 4I Expression was detected in bilateral domains of the anterior neural ridge.

Specimen 4J: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: future forebrain Present Regionally restricted 4J Expression was detected in the commissural plate.
TS15: olfactory placode Present Regionally restricted 4J Expression was detected in lateral epithelial domains of developing nasal placodes.

Specimen 4M: embryonic day 8.25; Chrdtm1Emdr/Chrdtm1Emdr, Nogtm1Amc/Nog+ (more )
Note: ~ 5 somites.
Structure Level Pattern Image Note
TS12: anterior neural ridge Weak Regionally restricted 4M Affected mutant embryos have reduced expression in a single domain, fused at the midline.

Specimen 4N: embryonic day 9.5; Chrdtm1Emdr/Chrdtm1Emdr, Nogtm1Amc/Nog+ (more )
Structure Level Pattern Image Note
TS15: future forebrain Weak Regionally restricted 4N Only a medial expression domain with reduced levels was detected in the commissural plate.
TS15: olfactory placode Weak Regionally restricted 4N Only a medial expression domain with reduced levels was detected in the nasal placodes.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/25/2025
MGI 6.24
The Jackson Laboratory