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Gene Expression Data
Assay Details
Assay
Reference: J:324238 Lo M, et al., CNPY4 inhibits the Hedgehog pathway by modulating membrane sterol lipids. Nat Commun. 2022 May 3;13(1):2407
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:7312087
Gene symbol: Gli1
Gene name: GLI-Kruppel family member GLI1
Reporter: lacZ
Direct Detection
Results
Specimen 2a Gli1-LacZ E10.5 Control: embryonic day 10.5; Gli1tm2Alj/Gli1+ (more )
Structure Level Pattern Image Note
TS17: hindlimb bud Present 2a Gli1-LacZ E10.5 Control
Specimen 2a Gli1-LacZ E10.5 Cnpy4-/-: embryonic day 10.5; Cnpy4tm1Lex/Cnpy4tm1Lex, Gli1tm2Alj/Gli1+ (more )
Structure Level Pattern Image Note
TS17: hindlimb bud Present 2a Gli1-LacZ E10.5 Cnpy4-/-
Specimen 2a Gli1-LacZ E11.5 Control: embryonic day 11.5; Gli1tm2Alj/Gli1+ (more )
Structure Level Pattern Image Note
TS19: hindlimb bud Present 2a Gli1-LacZ E11.5 Control
Specimen 2a Gli1LacZ E11.5 Cnpy4-/-: embryonic day 11.5; Cnpy4tm1Lex/Cnpy4tm1Lex, Gli1tm2Alj/Gli1+ (more )
Structure Level Pattern Image Note
TS19: hindlimb bud Present Regionally restricted 2a Gli1-LacZ E11.5 Cnpy4-/- Expression domain expanded anteriorly.
Specimen 2a Gli1-LacZ E12.5 Control: embryonic day 12.5; Gli1tm2Alj/Gli1+ (more )
Structure Level Pattern Image Note
TS20: hindlimb Present 2a Gli1-LacZ E12.5 Control
Specimen 2a Gli1-LacZ E12.5 Cnpy4-/-: embryonic day 12.5; Cnpy4tm1Lex/Cnpy4tm1Lex, Gli1tm2Alj/Gli1+ (more )
Structure Level Pattern Image Note
TS20: hindlimb Present Regionally restricted 2a Gli1-LacZ E12.5 Cnpy4-/- Ectopic expression in anterior domains.
Specimen S3 Gli1-LacZ E10.5: embryonic day 10.5; Cnpy4tm1Lex/Cnpy4tm1Lex, Gli1tm2Alj/Gli1+ (more )
Structure Level Pattern Image Note
TS17: hindlimb bud Weak Regionally restricted S3_Gli1-LacZ E10.5 Authors report reduced expresson in a minority of mutant hindlimb buds.
Specimen S3 Gli1-LacZ E11.5: embryonic day 11.5; Cnpy4tm1Lex/Cnpy4tm1Lex, Gli1tm2Alj/Gli1+ (more )
Structure Level Pattern Image Note
TS19: hindlimb bud Weak Regionally restricted S3_Gli1-LacZ E11.5 Authors report reduced expresson in a minority of mutant hindlimb buds.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory