About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:308709 Duran Alonso MB, et al., Meis2 Is Required for Inner Ear Formation and Proper Morphogenesis of the Cochlea. Front Cell Dev Biol. 2021;9:679325
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7294206
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: Anti-Sox2 (Y-17; sc-17320)
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen 5C: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: semicircular canal Present Regionally restricted 5C Expressed in the posterior, lateral, and anterior cristae.
TS22: cochlear duct Present 5C
TS22: macula of saccule Present 5C
TS22: macula of utricle Present 5C

Specimen 5D: embryonic day 14.0; Mafbtm1.1(cre)Kmm/Mafb+, Meis2tm1.1Mtor/Meis2tm1.1Mtor (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: macula of saccule Present 5D Similar as in the control.
TS22: macula of utricle Present 5D Similar as in the control.
TS22: semicircular canal Present 5D Similar as in the control.
TS22: cochlear duct Present 5D A small patch of expression at the basal portion of the cochlea, confirming the shortening of the cochlear duct.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support.
last database update
03/25/2025
MGI 6.24
The Jackson Laboratory