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Gene Expression Data
Assay Details
Assay
Reference: J:308709 Duran Alonso MB, et al., Meis2 Is Required for Inner Ear Formation and Proper Morphogenesis of the Cochlea. Front Cell Dev Biol. 2021;9:679325
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7287917
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: Anti-Sox2 (Y-17; sc-17320)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 4M: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: otocyst Present Regionally restricted 4M Expressed in the ventral region.
Specimen 4N: embryonic day 11.5; Meis2tm1.1Mtor/Meis2tm1.1Mtor, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: otocyst Present 4N Reduced expression domain that correlated with the smaller size of the otic vesicle in the mutant.
Specimen 5E: embryonic day 14.0 (more )
Structure Level Pattern Image Note
TS22: cochlear duct epithelium Present Regionally restricted 5E Expressed in the prosensory region.
Specimen 5F: embryonic day 14.0; Mafbtm1.1(cre)Kmm/Mafb+, Meis2tm1.1Mtor/Meis2tm1.1Mtor (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: cochlear duct epithelium Present Regionally restricted 5F Expressed in the prosensory region, similar as in the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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