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Gene Expression Data
Assay Details
Assay
Reference: J:321550 Ting MC, et al., Embryonic requirements for Tcf12 in the development of the mouse coronal suture. Development. 2022 Jan 1;149(1):dev199575
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7284988
Gene symbol: Grem1
Gene name: gremlin 1, DAN family BMP antagonist
Antibody: GREM1 Polyclonal Antibody (PA5-47973)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 4D: embryonic day 14.5 (more )
Note: Double labeled: green - Grem1; magenta - Sp7 (assay MGI:7284989).
Structure Level Pattern Image Note
TS22: frontal bone primordium Present Regionally restricted 4D Expression is in osteoprogenitor cells.
TS22: parietal bone primordium Present Regionally restricted 4D Expression is in osteoprogenitor cells.
Specimen 4E: embryonic day 14.5; Tcf12tm3Zhu/Tcf12tm3Zhu (more )
Note: Double labeled: green - Grem1; magenta - Sp7 (assay MGI:7284989).
Structure Level Pattern Image Note
TS22: frontal bone primordium Present Regionally restricted 4E In this mutant there is a reduction of positive cells above the frontal bone compared to wild-type.
TS22: parietal bone primordium Present Regionally restricted 4E In this mutant there is a reduction in positive cells above and below the parietal bone compared to wild-type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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