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Gene Expression Data
Assay Details
Assay
Reference: J:306226 Firulli BA, et al., HAND1 loss-of-function within the embryonic myocardium reveals survivable congenital cardiac defects and adult heart failure. Cardiovasc Res. 2020 Mar 1;116(3):605-618
Assay type: RNA in situ
MGI Accession ID: MGI:7284893
Gene symbol: Hand1
Gene name: heart and neural crest derivatives expressed 1
Results
Specimen 1A: embryonic day 10.5; Hand1tm2Eno/Hand1tm2Eno (more )
Structure Level Pattern Image Note
TS17: primitive ventricle Present Regionally restricted 1A Expression in left ventricle.
TS17: branchial arch Present 1A Expression within pharyngeal arches.
Specimen 1B: embryonic day 10.5; Hand1tm2Eno/Hand1tm2Eno, Nkx2-5tm1(cre)Rjs/Nkx2-5+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: primitive ventricle Absent 1B No expression in left ventricle.
TS17: branchial arch Present 1B Expression within pharyngeal arches.
Specimen 1C: embryonic day 10.5; Hand1tm2Eno/Hand1tm2Eno (more )
Structure Level Pattern Image Note
TS17: primitive ventricle Present Regionally restricted 1C Expression in left ventricle.
TS17: branchial arch Present 1C Expression within pharyngeal arches.
Specimen 1D: embryonic day 10.5; Hand1tm2Eno/Hand1tm2Eno, Tg(Myh6-cre)2182Mds/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: primitive ventricle Absent 1D No expression in left ventricle.
TS17: branchial arch Present 1D Expression within pharyngeal arches.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory