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Gene Expression Data
Assay Details
Assay
Reference: J:259302 Teratake Y, et al., Transcriptional repression of p27 is essential for murine embryonic development. Sci Rep. 2016 May 19;6:26244
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7284267
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-activated caspase3
Detection system: Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
Results
Specimen 3B Nczf+/+ caspase3: embryonic day 6.5 (more )
Structure Level Pattern Image Note
TS9: embryo Absent 3B caspase3 +/+ No sign of apoptosis at this stage.

Specimen 3B Nczf-/- caspase3: embryonic day 6.5; Zfp949tm1Htno/Zfp949tm1Htno (more )
Structure Level Pattern Image Note
TS9: embryo Absent 3B caspase3 -/- No difference compared to wildtype.

Specimen 5C E9.5 p27-/- Nczf+/+: embryonic day 9.5; Cdkn1btm1Kin/Cdkn1btm1Kin (more )
Structure Level Pattern Image Note
TS15: future brain Absent 5C E9.5 +/+

Specimen 5C E9.5 p27-/- Nczf-/-: embryonic day 9.5; Cdkn1btm1Kin/Cdkn1btm1Kin, Zfp949tm1Htno/Zfp949tm1Htno (more )
Structure Level Pattern Image Note
TS15: future brain Absent 5C E9.5 -/-

Specimen 5C E11.5 p27-/- Nczf+/+: embryonic day 11.5; Cdkn1btm1Kin/Cdkn1btm1Kin (more )
Structure Level Pattern Image Note
TS19: brain Absent 5C E11.5 +/+

Specimen 5C E11.5 p27-/- Nczf-/-: embryonic day 11.5; Cdkn1btm1Kin/Cdkn1btm1Kin, Zfp949tm1Htno/Zfp949tm1Htno (more )
Structure Level Pattern Image Note
TS19: forebrain Present 5C E11.5 -/- , 5C E11.5 -/- inset
TS19: midbrain Present 5C E11.5 -/- , 5C E11.5 -/- inset


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/14/2024
MGI 6.23
The Jackson Laboratory