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Gene Expression Data
Assay Details
Assay
Reference: J:297073 Chen Z, et al., The vascular endothelial cell-expressed prion protein doppel promotes angiogenesis and blood-brain barrier development. Development. 2020 Sep 23;147(18):dev193094
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7281339
Gene symbol: Prnd
Gene name: prion like protein doppel
Antibody: doppel antibody
Detection system: Secondary antibody
Results
Specimen 1E E14.5: embryonic day 14.5 (more )
Structure Cell Type Level Pattern Image Note
TS22: brain blood vessel blood vessel endothelial cell Present 1E E14.5 Expression in blood vessels of brain as early as E14.5.
Specimen 1E E17.5: embryonic day 17.5 (more )
Structure Cell Type Level Pattern Image Note
TS25: brain blood vessel blood vessel endothelial cell Present 1E E17.5 Expression persisted in later embryonic stages.
Specimen 1E P7: postnatal day 7 (more )
Structure Cell Type Level Pattern Image Note
TS28: brain blood vessel blood vessel endothelial cell Present 1E P7
Specimen 1E P21: postnatal day 21 (more )
Structure Cell Type Level Pattern Image Note
TS28: brain blood vessel blood vessel endothelial cell Ambiguous 1E P21 Authors diminished in most blood vessels at P21.
Specimen S2C: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: cerebellum blood vessel endothelial cell Present S2C
Specimen S2D: postnatal adult; Prndtm1Sbp/Prndtm1Sbp (more )
Structure Level Pattern Image Note
TS28: cerebellum Absent S2D
Specimen S2E: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: cerebral cortex blood vessel endothelial cell Present S2E
Specimen S2F: postnatal adult; Prndtm1Sbp/Prndtm1Sbp (more )
Structure Level Pattern Image Note
TS28: cerebral cortex Absent S2F
Specimen S2G: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: intestine blood vessel endothelial cell Present S2G Expression in intestinal microvilli.
Specimen S2H: postnatal adult; Prndtm1Sbp/Prndtm1Sbp (more )
Structure Level Pattern Image Note
TS28: intestine Absent S2H
Specimen S2I: postnatal adult (more )
Structure Cell Type Level Pattern Image Note
TS28: Sertoli cell Sertoli cell Present S2I
Specimen S2J: postnatal adult; Prndtm1Sbp/Prndtm1Sbp (more )
Structure Level Pattern Image Note
TS28: testis Absent S2J
Specimen S9B: postnatal day 7 (more )
Structure Cell Type Level Pattern Image Note
TS28: retina blood vessel retinal blood vessel endothelial cell Present S9B Expression in sprouting blood vessels of primary vascular plexus.
Specimen S9C: postnatal day 14 (more )
Structure Cell Type Level Pattern Image Note
TS28: retina blood vessel retinal blood vessel endothelial cell Present S9C Expression in secondary vascular plexi.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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12/30/2025
MGI 6.24 		The Jackson Laboratory