Prnd^tm1Sbp
Targeted Allele Detail

Summary

• Symbol: Prnd^tm1Sbp
• Name: prion like protein doppel; targeted mutation 1, Stanley B Prusiner
• MGI ID: MGI:6508088
• Gene: Prnd Location: Chr2:131792781-131798050 bp, + strand Genetic Position: Chr2, 64.07 cM
• Alliance: Prnd^tm1Sbp page

Mutation origin

• Germline Transmission: Earliest citation of germline transmission: J:300211
• Parent Cell Line: Not Specified (ES Cell)
• Strain of Origin: Not Specified

Mutation description

• Allele Type: Targeted (Null/knockout)
• Mutations: Insertion, Intragenic deletion
• A loxP-flanked PGK/neomycin cassette replaced the entireopen reading frame (ORF) within exon 2. (J:300211)

Expression

In Mice Carrying this Mutation:

30 assay results

Find Mice (IMSR)

• Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
• Carrying this Mutation: Mouse Strains: 0 strains available Cell Lines: 0 lines available
• Carrying any Prnd Mutation: 6 strains or lines available

References

• Original: J:300211 Tamguney G, et al., Genes contributing to prion pathogenesis. J Gen Virol. 2008 Jul;89(Pt 7):1777-1788
• All: 1 reference(s)