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Gene Expression Data
Assay Details
Assay
Reference: J:190555 Yoon Y, et al., Conditional Aurora A deficiency differentially affects early mouse embryo patterning. Dev Biol. 2012 Nov 1;371(1):77-85
Assay type: RNA in situ
MGI Accession ID: MGI:7264812
Gene symbol: T
Gene name: brachyury, T-box transcription factor T
Probe: T cDNA9
Probe preparation: labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 3B Control: embryonic day 6.5; Aurkatm1.1Tvd/Aurka+, Edil3Tg(Sox2-cre)1Amc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS9: primitive streak Present 3B Control
TS9: extraembryonic ectoderm Present Regionally restricted 3B Control Expression in distal portion of extraembryonic ectoderm.
Specimen 3B Epi-KO: embryonic day 6.5; Aurkatm1.1Tvd/Aurkatm1.2Tvd, Edil3Tg(Sox2-cre)1Amc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS9: primitive streak Present Regionally restricted 3B Epi-KO Expression in small area on one side of epiblast, indicating that primitive streak was specified.
TS9: extraembryonic ectoderm Present Regionally restricted 3B Epi-KO Expression in distal extraembryonic ectoderm.
Specimen 6E Control: embryonic day 6.5; Aurkatm1.1Tvd/Aurka+, Tg(Ttr-cre)1Hadj/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS9: primitive streak Present 6E Control
Specimen 6E VE-KO: embryonic day 6.5; Aurkatm1.1Tvd/Aurkatm1.2Tvd, Tg(Ttr-cre)1Hadj/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS9: primitive streak Present Regionally restricted 6E VE-KO Expression expanded anteriorly around epiblast junction with extraembryonic ectoderm
Specimen 6F Control: embryonic day 6.5; Aurkatm1.1Tvd/Aurka+, Tg(Ttr-cre)1Hadj/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS9: primitive streak Present 6F Control
Specimen 6F VE-KO: embryonic day 6.5; Aurkatm1.1Tvd/Aurkatm1.2Tvd, Tg(Ttr-cre)1Hadj/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS9: primitive streak Present Regionally restricted 6F VE-KO Expression expanded anteriorly around epiblast junction with extraembryonic ectoderm
Specimen 6G Control: embryonic day 6.5; Aurkatm1.1Tvd/Aurka+, Tg(Ttr-cre)1Hadj/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS9: primitive streak Present 6G Control
Specimen 6G VE-KO: embryonic day 6.5; Aurkatm1.1Tvd/Aurkatm1.2Tvd, Tg(Ttr-cre)1Hadj/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS9: primitive streak Present Regionally restricted 6G VE-KO Expression properly localized on posterior side of embryo.
Specimen 6H Control: embryonic day 6.5; Aurkatm1.1Tvd/Aurka+, Tg(Ttr-cre)1Hadj/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS9: primitive streak Present 6H Control
Specimen 6H VE-KO: embryonic day 6.5; Aurkatm1.1Tvd/Aurkatm1.2Tvd, Tg(Ttr-cre)1Hadj/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS9: primitive streak Present Regionally restricted 6H VE-KO Expression properly localized on posterior side of embryo.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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