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T cDNA9 Probe Detail
Nucleotide
Probe/Clone
  • Name
    T cDNA9
  • Sequence Type
    cDNA
  • ID
    MGI:2449092
  • Region Covered
    spans nucleotides 1 to 1764 of pme 75
  • Parent Clone
  • Insert Size
    1.764 kb
Source
  • Species
    mouse, laboratory
  • Age
    embryonic day 8.5
Genes
T brachyury, T-box transcription factor T
Expression
  • Assay Results
    239
Sequences
References
J:1975 Herrmann BG, Expression pattern of the Brachyury gene in whole-mount TWis/TWis mutant embryos. Development. 1991 Nov;113(3):913-7
J:3684 Smith DE, et al., Isolation of Sna, a mouse gene homologous to the Drosophila genes snail and escargot: its expression pattern suggests multiple roles during postimplantation development [published erratum appears in Development 1993 Mar;117(3):preceding table of contents]. Development. 1992 Dec;116(4):1033-9
J:16484 Dietrich S, et al., Altered Pax gene expression in murine notochord mutants: the notochord is required to initiate and maintain ventral identity in the somite. Mech Dev. 1993 Dec;44(2-3):189-207
J:19895 Ang SL, et al., HNF-3 beta is essential for node and notochord formation in mouse development. Cell. 1994 Aug 26;78(4):561-74
J:25248 Conlon RA, et al., Notch1 is required for the coordinate segmentation of somites. Development. 1995 May;121(5):1533-45
J:27183 Duyao MP, et al., Inactivation of the mouse Huntington's disease gene homolog Hdh. Science. 1995 Jul 21;269(5222):407-10
J:29276 Acampora D, et al., Forebrain and midbrain regions are deleted in Otx2-/- mutants due to a defective anterior neuroectoderm specification during gastrulation. Development. 1995 Oct;121(10):3279-90
J:29978 Furuta Y, et al., Mesodermal defect in late phase of gastrulation by a targeted mutation of focal adhesion kinase, FAK. Oncogene. 1995 Nov 16;11(10):1989-95
J:30828 Ang SL, et al., A targeted mouse Otx2 mutation leads to severe defects in gastrulation and formation of axial mesoderm and to deletion of rostral brain. Development. 1996 Jan;122(1):243-52
J:33755 Clements D, et al., Distinct regulatory control of the Brachyury gene in axial and non-axial mesoderm suggests separation of mesoderm lineages early in mouse gastrulation. Mech Dev. 1996 May;56(1-2):139-49
J:36233 Larue L, et al., A role for cadherins in tissue formation. Development. 1996 Oct;122(10):3185-94
J:44237 Goh KL, et al., Mesodermal defects and cranial neural crest apoptosis in alpha5 integrin-null embryos. Development. 1997 Nov;124(21):4309-19
J:46377 Biben C, et al., Murine cerberus homologue mCer-1: a candidate anterior patterning molecule. Dev Biol. 1998 Feb 15;194(2):135-51
J:47700 Greene ND, et al., Abnormalities of floor plate, notochord and somite differentiation in the loop-tail (Lp) mouse: a model of severe neural tube defects. Mech Dev. 1998 Apr;73(1):59-72
J:47940 Ishijima J, et al., Dominant lethality of the mouse skeletal mutation tail-short (Ts) is determined by the Ts allele from mating partners. Genomics. 1998 May 1;49(3):341-50
J:48372 Tang SJ, et al., The Tlx-2 homeobox gene is a downstream target of BMP signalling and is required for mouse mesoderm development. Development. 1998 May;125(10):1877-87
J:49657 Dufort D, et al., The transcription factor HNF3beta is required in visceral endoderm for normal primitive streak morphogenesis. Development. 1998 Aug;125(16):3015-25
J:50519 Gotz J, et al., Delayed embryonic lethality in mice lacking protein phosphatase 2A catalytic subunit Calpha. Proc Natl Acad Sci U S A. 1998 Oct 13;95(21):12370-5
J:51989 Suda Y, et al., Functional equivalency between Otx2 and Otx1 in development of the rostral head. Development. 1999 Feb;126(4):743-57
J:57670 Mishina Y, et al., Multiple roles for activin-like kinase-2 signaling during mouse embryogenesis. Dev Biol. 1999 Sep 15;213(2):314-26
J:73507 Heyer J, et al., Postgastrulation Smad2-deficient embryos show defects in embryo turning and anterior morphogenesis. Proc Natl Acad Sci U S A. 1999 Oct 26;96(22):12595-600
J:64021 Lin X, et al., Disruption of gastrulation and heparan sulfate biosynthesis in EXT1-deficient mice. Dev Biol. 2000 Aug 15;224(2):299-311
J:68215 Xue Y, et al., Mesodermal patterning defect in mice lacking the Ste20 NCK interacting kinase (NIK). Development. 2001 May;128(9):1559-72
J:74631 Tian E, et al., Otx2 is required to respond to signals from anterior neural ridge for forebrain specification. Dev Biol. 2002 Feb 15;242(2):204-23
J:77125 Norris DP, et al., The Foxh1-dependent autoregulatory enhancer controls the level of Nodal signals in the mouse embryo. Development. 2002 Jul;129(14):3455-68
J:79513 Hayashi K, et al., SMAD1 signaling is critical for initial commitment of germ cell lineage from mouse epiblast. Mech Dev. 2002 Oct;118(1-2):99
J:80018 Przemeck GK, et al., Node and midline defects are associated with left-right development in Delta1 mutant embryos. Development. 2003 Jan;130(1):3-13
J:85760 Yan J, et al., COP9 signalosome subunit 3 is essential for maintenance of cell proliferation in the mouse embryonic epiblast. Mol Cell Biol. 2003 Oct;23(19):6798-808
J:86144 Miura S, et al., Whole-embryo culture of E5.5 mouse embryos: development to the gastrulation stage. Genesis. 2003 Sep;37(1):38-43
J:91012 Kurokawa D, et al., Regulation of Otx2 expression and its functions in mouse epiblast and anterior neuroectoderm. Development. 2004 Jul;131(14):3307-17
J:148693 Narimatsu M, et al., Regulation of planar cell polarity by Smurf ubiquitin ligases. Cell. 2009 Apr 17;137(2):295-307
J:173623 Biechele S, et al., Porcupine homolog is required for canonical Wnt signaling and gastrulation in mouse embryos. Dev Biol. 2011 Jul 15;355(2):275-85
J:190555 Yoon Y, et al., Conditional Aurora A deficiency differentially affects early mouse embryo patterning. Dev Biol. 2012 Nov 1;371(1):77-85
J:192194 Tortelote GG, et al., Wnt3 function in the epiblast is required for the maintenance but not the initiation of gastrulation in mice. Dev Biol. 2013 Feb 1;374(1):164-73
J:254332 Acharya D, et al., KAT-Independent Gene Regulation by Tip60 Promotes ESC Self-Renewal but Not Pluripotency. Cell Rep. 2017 Apr 25;19(4):671-679

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Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
05/21/2024
MGI 6.23
The Jackson Laboratory