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Gene Expression Data
Assay Details
Assay
Reference: J:248980 Guo H, et al., Trinucleotide repeat containing 6c (TNRC6c) is essential for microvascular maturation during distal airspace sacculation in the developing lung. Dev Biol. 2017 Oct 1;430(1):214-223
Assay type: Immunohistochemistry
MGI Accession ID: MGI:7258076
Gene symbol: Sftpc
Gene name: surfactant associated protein C
Antibody: anti-proSP-C
Detection system: Secondary antibody coupled to Alexa Fluor
Results
Specimen 2A Alveolar WT pSftpc: embryonic day 18.5 (more )
Note: Triple labeled: green - Sftpc; red - Pdpn (assay MGI:7258078); blue - DAPI.
Structure Cell Type Level Pattern Image Note
TS26: lung alveolus pulmonary alveolar type 2 cell Present 2A Alveolar WT +DAPI , 2A Alveolar WT pSftpc Expression in alveolar epithelial type 2 (AT2) cells in distal saccules.
Specimen 2A Alveolar TNRC6c-/- pSftpc: embryonic day 18.5; Tnrc6cGt(IST11346C2)Tigm/Tnrc6cGt(IST11346C2)Tigm (more )
Note: Triple labeled: green - Sftpc; red - Pdpn (assay MGI:7258078); blue - DAPI.
Structure Cell Type Level Pattern Image Note
TS26: lung alveolus pulmonary alveolar type 2 cell Present 2A Alveolar TNRC6c-/- pSftpc , 2A Alveolar TNRC6c-/- +DAPI Expression present and properly localized within mutant lungs, in a similar to that of wild type.
Specimen 2B Alveolar WT pSftpc: postnatal day 0 (more )
Note: Triple labeled: green - Sftpc; red - Pdpn (assay MGI:7258078); blue - DAPI.
Structure Cell Type Level Pattern Image Note
TS27: lung alveolus pulmonary alveolar type 2 cell Present 2B Alveolar WT +DAPI , 2B Alveolar WT pSftpc Expression in alveolar epithelial type 2 (AT2) cells in distal saccules.
Specimen 2B Alveolar TNRC6c-/- pSftpc: postnatal day 0; Tnrc6cGt(IST11346C2)Tigm/Tnrc6cGt(IST11346C2)Tigm (more )
Note: Triple labeled: green - Sftpc; red - Pdpn (assay MGI:7258078); blue - DAPI.
Structure Cell Type Level Pattern Image Note
TS27: lung alveolus pulmonary alveolar type 2 cell Present 2B Alveolar TNRC6c-/- +DAPI , 2B Alveolar TNRC6c-/- pSftpc Expression present and properly localized within mutant lungs, in a similar to that of wild type.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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