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Gene Expression Data
Assay Details
Assay
Reference: J:47640 Herbarth B, et al., Mutation of the Sry-related Sox10 gene in Dominant megacolon, a mouse model for human Hirschsprung disease. Proc Natl Acad Sci U S A. 1998 Apr 28;95(9):5161-5
Assay type: RNA in situ
MGI Accession ID: MGI:6842955
Gene symbol: Sox10
Gene name: SRY (sex determining region Y)-box 10
Probe: Sox10 probe30
Probe preparation: Antisense labelled with S35 RNA
Results
Specimen 3d Dom/Dom: embryonic day 14.5; Sox10Dom/Sox10Dom (more )
Structure Level Pattern Image Note
TS22: intestine Absent 3d Dom/Dom

Specimen 3d Dom/+: embryonic day 14.5; Sox10Dom/Sox10+ (more )
Structure Level Pattern Image Note
TS22: intestine Present Single cells 3d Dom/+ Few expressing cells detected in intestine of heterozygotes.

Specimen 3d +/+: embryonic day 14.5 (more )
Structure Level Pattern Image Note
TS22: enteric nervous system Present 3d +/+ Expression in cells within enteric nervous system.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory