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Gene Expression Data
Assay Details
Assay
Reference: J:307192 Yadav PS, et al., Stat3 loss in mesenchymal progenitors causes Job syndrome-like skeletal defects by reducing Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2020100118
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6831092
Gene symbol: Sp7
Gene name: Sp7 transcription factor 7
Antibody: Anti-Sp7/Osterix antibody (ab22552)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 6B Prrx1Cre;Stat3C/+: postnatal day 0; Stat3tm1Flv/Stat3+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: humerus Present 6B Sp7 Prrx1Cre;Stat3C/+
Specimen 6B Prrx1Cre;Stat3C/C: postnatal day 0; Stat3tm1Flv/Stat3tm1Flv, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: humerus Weak 6B Sp7 Prrx1Cre;Stat3C/C
Specimen 6B Prrx1Cre;Stat3C/C:Lrp5+/-: postnatal day 0; Lrp5tm2Mawa/Lrp5+, Stat3tm1Flv/Stat3tm1Flv, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: humerus Present 6B Sp7 Prrx1Cre;Stat3C/C;Lrp5-/+ Expression in this mutant is similar to controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory