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Gene Expression Data
Assay Details
Assay
Reference: J:307192 Yadav PS, et al., Stat3 loss in mesenchymal progenitors causes Job syndrome-like skeletal defects by reducing Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2020100118
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6831058
Gene symbol: Sost
Gene name: sclerostin
Antibody: anti-Sost (ab63097)
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen S6C P5 Prrx1Cre;Stat3C/+: postnatal day 5; Stat3tm1Flv/Stat3+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: humerus Present Regionally restricted S6C P5 Prrx1Cre;Stat3C/+ Expression is in osteocytes.
Specimen S6C P5 Prrx1Cre;Stat3C/C: postnatal day 5; Stat3tm1Flv/Stat3tm1Flv, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: humerus Strong S6C P5 Prrx1Cre;Stat3C/C
Specimen S6C P21 Prrx1Cre;Stat3C/+: postnatal day 21; Stat3tm1Flv/Stat3+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: humerus Present Regionally restricted S6C P21 Prrx1Cre;Stat3C/+ Expression is in osteocytes.
Specimen S6C P21 Prrx1Cre;Stat3C/C: postnatal day 21; Stat3tm1Flv/Stat3tm1Flv, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: humerus Strong S6C P21 Prrx1Cre;Stat3C/C
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory