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Gene Expression Data
Assay Details
Assay
Reference: J:307192 Yadav PS, et al., Stat3 loss in mesenchymal progenitors causes Job syndrome-like skeletal defects by reducing Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2020100118
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6831037
Gene symbol: Col10a1
Gene name: collagen, type X, alpha 1
Antibody: anti-Col10a1 (A6889)
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen S2A Prrx1Cre;Stat3C/+: embryonic day 16.5; Stat3tm1Flv/Stat3+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: humerus Present Regionally restricted S2A Col10a1 E16.5 Prrx1Cre;Stat3C/+ Expression is in hypertrophic chondrocytes.
Specimen S2A Prrx1Cre;Stat3C/C: embryonic day 16.5; Stat3tm1Flv/Stat3tm1Flv, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: humerus Present Regionally restricted S2A Col10a1 E16.5 Prrx1Cre;Stat3C/C Expression in this mutant is the same as in controls.
Specimen S2A P0 Prrx1Cre;Stat3C/+: postnatal day 0; Stat3tm1Flv/Stat3+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: humerus Present Regionally restricted S2A Col10a1 P0 Prrx1Cre;Stat3C/+ Expression is in hypertrophic chondrocytes.
Specimen S2A P0 Prrx1Cre;Stat3C/C: postnatal day 0; Stat3tm1Flv/Stat3tm1Flv, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: humerus Present Regionally restricted S2A Col10a1 P0 Prrx1Cre;Stat3C/C Expression in this mutant has expanded in this mutant compared to controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory