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Gene Expression Data
Assay Details
Assay
Reference: J:307192 Yadav PS, et al., Stat3 loss in mesenchymal progenitors causes Job syndrome-like skeletal defects by reducing Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2020100118
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6831025
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved caspase-3 (Asp175) (5A1E; #9664)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Assay notes: Quantification of Cleaved-Caspase cells in the marrow area are shown in the right panel.
Results
Specimen S1D Prrx1Cre;Stat3C/+: postnatal day 0; Stat3tm1Flv/Stat3+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: bone marrow Present S1D Prrx1Cre;Stat3C/+ bottom , S1D Prrx1Cre;Stat3C/+ top
Specimen S1D Prrx1Cre;Stat3C/C: postnatal day 0; Stat3tm1Flv/Stat3tm1Flv, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: bone marrow Strong S1D Prrx1Cre;Stat3C/C bottom , S1D Prrx1Cre;Stat3C/C top
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory