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Gene Expression Data
Assay Details
Assay
Reference: J:307192 Yadav PS, et al., Stat3 loss in mesenchymal progenitors causes Job syndrome-like skeletal defects by reducing Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2020100118
Assay type: RNA in situ
MGI Accession ID: MGI:6830998
Gene symbol: Col1a1
Gene name: collagen, type I, alpha 1
Probe: Col1a1 probe16
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2B E16.5 Prrx1Cre;Stat3C/+: embryonic day 16.5; Stat3tm1Flv/Stat3+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: humerus Present Regionally restricted 2B E16.5 Prrx1Cre;Stat3C/+ Expression is in osteoblasts.

Specimen 2B E16.5 Prrx1Cre;Stat3C/C: embryonic day 16.5; Stat3tm1Flv/Stat3tm1Flv, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: humerus Weak Regionally restricted 2B E16.5 Prrx1Cre;Stat3C/C

Specimen 2B P0 Prrx1Cre;Stat3C/+: postnatal day 0; Stat3tm1Flv/Stat3+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: humerus Present Regionally restricted 2B P0 Prrx1Cre;Stat3C/+ Expression is in osteoblasts.

Specimen 2B P0 Prrx1Cre;Stat3C/C: postnatal day 0; Stat3tm1Flv/Stat3tm1Flv, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: humerus Weak Regionally restricted 2B P0 Prrx1Cre;Stat3C/C

Specimen 3D OsxCre;Stat3C/+: embryonic day 16.5; Stat3tm1Flv/Stat3+, Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: humerus Present Regionally restricted 3D Col1a1 OsxCre;Stat3C/+ Expression is in osteoblasts.

Specimen 3D OsxCre;Stat3C/C: embryonic day 16.5; Stat3tm1Flv/Stat3tm1Flv, Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: humerus Weak Regionally restricted 3D Col1a1 OsxCre;Stat3C/C

Specimen 3E OsxCre;Stat3C/+: embryonic day 18.5; Stat3tm1Flv/Stat3+, Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: humerus Present Regionally restricted 3E Col1a1 OsxCre;Stat3C/+ Expression is in osteoblasts.

Specimen 3E OsxCre;Stat3C/C: embryonic day 18.5; Stat3tm1Flv/Stat3tm1Flv, Tg(Sp7-tTA,tetO-EGFP/cre)1Amc/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS26: humerus Weak 3E Col1a1 OsxCre;Stat3C/C


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory