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Gene Expression Data
Assay Details
Assay
Reference: J:307192 Yadav PS, et al., Stat3 loss in mesenchymal progenitors causes Job syndrome-like skeletal defects by reducing Wnt/beta-catenin signaling. Proc Natl Acad Sci U S A. 2021 Jun 29;118(26):e2020100118
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6830994
Gene symbol: Spp1
Gene name: secreted phosphoprotein 1
Antibody: anti-osteopontin (AF808)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 2C E16.5 Prrx1Cre;Stat3C/+: embryonic day 16.5; Stat3tm1Flv/Stat3+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: humerus Present Regionally restricted 2C E16.5 Prrx1Cre;Stat3C/+ Expression is in osteoblasts.
Specimen 2C E16.5 Prrx1Cre;Stat3C/C: embryonic day 16.5; Stat3tm1Flv/Stat3tm1Flv, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS24: humerus Weak Regionally restricted 2C E16.5 Prrx1Cre;Stat3C/C
Specimen 2C P0 Prrx1Cre;Stat3C/+: postnatal day 0; Stat3tm1Flv/Stat3+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: humerus Present Regionally restricted 2C P0 Prrx1Cre;Stat3C/+ Expression is in osteoblasts.
Specimen 2C P0 Prrx1Cre;Stat3C/C: postnatal day 0; Stat3tm1Flv/Stat3tm1Flv, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: humerus Weak Regionally restricted 2C P0 Prrx1Cre;Stat3C/C
Specimen 5F Prrx1Cre;Stat3C/+: postnatal day 0; Stat3tm1Flv/Stat3+, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: humerus Present Regionally restricted 5F Opn Prrx1Cre;Stat3C/+ Expression is in osteoblasts.
Specimen 5F Prrx1Cre;Stat3C/C: postnatal day 0; Stat3tm1Flv/Stat3tm1Flv, Tg(Prrx1-cre)1Cjt/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: humerus Weak Regionally restricted 5F Opn Prrx1Cre;Stat3C/C
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory