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Gene Expression Data
Assay Details
Assay
Reference: J:312349 van Ineveld RL, et al., LGR6 marks nephron progenitor cells. Dev Dyn. 2021 Nov;250(11):1568-1583
Assay type: Recombinase reporter
MGI Accession ID: MGI:6818670
Gene symbol: Lgr6
Gene name: leucine-rich repeat-containing G protein-coupled receptor 6
Reporter: tdTomato
Direct Detection
Assay notes: mice were injected with tamoxifen at indicated time
Results
Specimen Fig5C: postnatal day 3; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Conditional mutant. TAM induction at P1
Structure Level Pattern Image Note
TS27: renal cortex Present Single cells 5C P3
Specimen Fig5D: postnatal day 3; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Conditional mutant. TAM induction at P1
Structure Level Pattern Image Note
TS27: comma-shaped body Present Single cells 5D P3
TS27: s-shaped body Present Single cells 5D P3
Specimen Fig5E: postnatal day 3; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Conditional mutant. TAM induction at P1
Structure Level Pattern Image Note
TS27: cap mesenchyme Present 5E P3
TS27: pretubular aggregate Present 5E P3
TS27: renal vesicle Present 5E P3
Specimen Fig5G: postnatal day 7; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Conditional mutant. TAM induction at P1
Structure Level Pattern Image Note
TS28: kidney outer cortex Present 5G P7
Specimen Fig5H: postnatal day 7; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Conditional mutant. TAM induction at P1
Structure Level Pattern Image Note
TS28: Bowman's capsule of mature renal corpuscle Present Single cells 5H P7
TS28: renal distal tubule Present Single cells 5H P7
TS28: renal proximal tubule Present Single cells 5H P7
Specimen Fig5I: postnatal day 14; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Conditional mutant. TAM induction at P1
Structure Level Pattern Image Note
TS28: Bowman's capsule of mature renal corpuscle Present Single cells 5I P14
TS28: renal distal tubule Present Single cells 5I P14
TS28: renal proximal tubule Present Single cells 5I P14
Specimen Fig5J: postnatal day 14; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Conditional mutant. TAM induction at P7
Structure Level Pattern Image Note
TS28: renal cortex Present Spotted 5J P14 very limited cells
TS28: renal medulla Present Spotted 5J P14 very limited cells
Specimen Fig6A: postnatal day 36; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Conditional mutant. TAM induction at P1
Structure Level Pattern Image Note
TS28: renal cortex Present 6A P36
TS28: renal medulla Present 6A P36
Specimen Fig6B: postnatal day 77; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Conditional mutant. TAM induction at P1
Structure Level Pattern Image Note
TS28: renal cortex Present 6B P77
TS28: renal medulla Present 6B P77
Specimen Fig6C: postnatal day 77; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Conditional mutant. TAM induction at P1
Structure Level Pattern Image Note
TS28: loop of Henle Present 6C P77
TS28: renal cortex Present 6C P77
TS28: renal medulla Present 6C P77
Specimen Fig6D: postnatal day 77; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Conditional mutant. TAM induction at P1
Structure Level Pattern Image Note
TS28: distal convoluted tubule Present 6D P77
TS28: loop of Henle Present 6D P77
TS28: renal connecting tubule Present 6D P77
Specimen Fig6E: postnatal day 77; Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+, Lgr6tm2.1(cre/ERT2)Cle/Lgr6+ (more )
Note: Conditional mutant. TAM induction at P1
Structure Level Pattern Image Note
TS28: collecting duct Absent 6E P77
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory