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Gene Expression Data
Assay Details
Assay
Reference: J:306246 He M, et al., Chloride channels regulate differentiation and barrier functions of the mammalian airway. Elife. 2020 Apr 14;9:e53085
Assay type: RNA in situ
MGI Accession ID: MGI:6781971
Gene symbol: Gp2
Gene name: glycoprotein 2 zymogen granule membrane
Probe: Mm-Gp2 (474641)
Probe preparation: Antisense
Visualized with: Fluorescence
Assay notes: RNAscope assay.
Results
Specimen 4B: postnatal day 3 (more )
Note: Triple labeled: teal - Gp2; magenta - Foxj1 (assay MGI:6781966); orange - Prr18 (assay MGI:6781972).
Structure Level Pattern Image Note
TS27: trachea epithelium Present Regionally restricted 4B Gp2/Foxj1 , 4B merge Although this is considered a secretory cell marker, expression is also seen in "hybrid" cells that express ciliated cell markers.
Specimen 4 S1A wt lower: postnatal newborn (more )
Note: Double labeled: green - Gp2; red - Foxj1 (assay MGI:6781966).
Structure Level Pattern Image Note
TS27: trachea epithelium Present Regionally restricted 4 S1A lower left Expression is seen in secretory cells and in "hybrid" cells that express both secretory and ciliated cell markers.
Specimen 4 S1A Pofut-/- lower: postnatal newborn; Pofut1tm1Pst/Pofut1tm1Pst (more )
Note: Double labeled: green - Gp2; red - Foxj1 (assay MGI:6781966).
Structure Level Pattern Image Note
TS27: trachea epithelium Present Regionally restricted 4 S1A lower right These mutants lack secretory cells (and, therefore, lack expression in them). Expression is retained in "hybrid" cells that express both secretory and ciliated cell markers.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory