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Gene Expression Data
Assay Details
Assay
Reference: J:289914 Brown RM 2nd, et al., Notch-mediated lateral induction is necessary to maintain vestibular prosensory identity during inner ear development. Dev Biol. 2020 Jun 1;462(1):74-84
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6761853
Gene symbol: Sox2
Gene name: SRY (sex determining region Y)-box 2
Antibody: anti-Sox2 (AB5603)
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 4B WT E9.5: embryonic day 9.5 (more )
Structure Level Pattern Image Note
TS15: otocyst epithelium Present 4B1-1
Specimen 4B cKO E9.5: embryonic day 9.5; Rbpjtm1.1Hon/Rbpjtm1Hon, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: otocyst epithelium Present 4B2-1 Similar as in the control.
Specimen 4B WT E10.5: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: otocyst epithelium Present Regionally restricted 4B1-2 Expressed in the vestibular and cochlear prosensory domains.
Specimen 4B cKO E10.5: embryonic day 10.5; Rbpjtm1.1Hon/Rbpjtm1Hon, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: otocyst epithelium Present Regionally restricted 4B2-2 Expressed in the ventral-most regions of the otocyst associated with the developing cochlear anlagen. No expression in the prosensory and neurosensory regions.
Specimen 4B WT E11.5 Anterior: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: otocyst epithelium Present Regionally restricted 4B1-3 Expressed in the vestibular and cochlear prosensory domains.
Specimen 4B cKO E11.5 Anterior: embryonic day 11.5; Rbpjtm1.1Hon/Rbpjtm1Hon, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: otocyst epithelium Present Regionally restricted 4B2-3 Expressed in the ventral-most regions of the otocyst associated with the developing cochlear anlagen. No expression in the prosensory and neurosensory regions.
Specimen 4B WT E11.5 Middle: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: otocyst epithelium Present Regionally restricted 4B1-4 Expressed in the vestibular and cochlear prosensory domains.
Specimen 4B cKO E11.5 Middle: embryonic day 11.5; Rbpjtm1.1Hon/Rbpjtm1Hon, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: otocyst epithelium Present Regionally restricted 4B2-4 Expressed in the ventral-most regions of the otocyst associated with the developing cochlear anlagen. No expression in the prosensory and neurosensory regions.
Specimen 4B WT E11.5 Posterior: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: otocyst epithelium Present Regionally restricted 4B1-5 Expressed in the vestibular and cochlear prosensory domains.
Specimen 4B cKO E11.5 Posterior: embryonic day 11.5; Rbpjtm1.1Hon/Rbpjtm1Hon, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: otocyst epithelium Present Regionally restricted 4B2-5 Expressed in the ventral-most regions of the otocyst associated with the developing cochlear anlagen. No expression in the prosensory and neurosensory regions.
Specimen 6A WT: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: otocyst epithelium Present Regionally restricted 6A WT left Expressed in the vestibular and cochlear prosensory domains.
Specimen 6A cKO: embryonic day 10.5; Rbpjtm1.1Hon/Rbpjtm1Hon, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: otocyst epithelium Present Regionally restricted 6A cKO left Expressed in the ventral-most regions of the otocyst associated with the developing cochlear anlagen. No expression in the prosensory and neurosensory regions.
Specimen 6B WT: embryonic day 11.5; Rbpjtm1.1Hon/Rbpjtm1Hon, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: otocyst epithelium Present Regionally restricted 6B WT left Expressed in the vestibular and cochlear prosensory domains.
Specimen 6B cKO: embryonic day 11.5; Rbpjtm1.1Hon/Rbpjtm1Hon, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: otocyst epithelium Present Regionally restricted 6B cKO left Expressed in the ventral-most regions of the otocyst associated with the developing cochlear anlagen. No expression in the prosensory and neurosensory regions.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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