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Gene Expression Data
Assay Details
Assay
Reference: J:289914 Brown RM 2nd, et al., Notch-mediated lateral induction is necessary to maintain vestibular prosensory identity during inner ear development. Dev Biol. 2020 Jun 1;462(1):74-84
Assay type: RNA in situ
MGI Accession ID: MGI:6761815
Gene symbol: Bmp4
Gene name: bone morphogenetic protein 4
Probe: Bmp4 probe97
Probe preparation: Antisense labelled with digoxigenin RNA
Visualized with: Alkaline phosphatase
Results
Specimen 2A WT E10.5 Anterior: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: otocyst epithelium Strong Regionally restricted 2A1-1 Expressed in the cristae prosensory domains.

Specimen 2A cKO E10.5 Anterior: embryonic day 10.5; Rbpjtm1.1Hon/Rbpjtm1Hon, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: otocyst epithelium Weak Regionally restricted 2A2-1 Expression in the cristae prosensory domain was reduced or absent compared with the control.

Specimen 2A WT E10.5 Lateral: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: otocyst epithelium Strong Regionally restricted 2A1-2 Expressed in the cristae and cochlear prosensory domains.

Specimen 2A cKO E10.5 Lateral: embryonic day 10.5; Rbpjtm1.1Hon/Rbpjtm1Hon, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: otocyst epithelium Weak Regionally restricted 2A2-2 Expression in the cristae prosensory domain was reduced or absent compared with the control. Expression in cochlear prosensory domain was similar as in the wild-type.

Specimen 2A WT E10.5 Posterior: embryonic day 10.5 (more )
Structure Level Pattern Image Note
TS17: otocyst epithelium Strong Regionally restricted 2A1-3 Expressed in the cristae and cochlear prosensory domains.

Specimen 2A cKO E10.5 Posterior: embryonic day 10.5; Rbpjtm1.1Hon/Rbpjtm1Hon, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: otocyst epithelium Weak Regionally restricted 2A2-3 Expression in the cristae prosensory domain was reduced or absent compared with the control. Expression in cochlear prosensory domain was similar as in the wild-type.

Specimen 2A WT E11.5 Anterior: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: otocyst epithelium Strong Regionally restricted 2A1-4 Expressed in the cristae prosensory domains.

Specimen 2A cKO E11.5 Anterior: embryonic day 11.5; Rbpjtm1.1Hon/Rbpjtm1Hon, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: otocyst epithelium Trace Regionally restricted 2A2-4 Expression in the cristae prosensory domain was almost completely absent compared with the control.

Specimen 2A WT E11.5 Lateral: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: otocyst epithelium Strong Regionally restricted 2A1-5 Expressed in the cristae and cochlear prosensory domains.

Specimen 2A cKO E11.5 Lateral: embryonic day 11.5; Rbpjtm1.1Hon/Rbpjtm1Hon, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: otocyst epithelium Trace Regionally restricted 2A2-5 Expression in the cristae prosensory domain was almost completely absent compared with the control. Expression in cochlear prosensory domain was similar as in the wild-type.

Specimen 2A WT E11.5 Posterior: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: otocyst epithelium Strong Regionally restricted 2A1-6 Expressed in the cristae and cochlear prosensory domains.

Specimen 2A cKO E11.5 Posterior: embryonic day 11.5; Rbpjtm1.1Hon/Rbpjtm1Hon, Tg(Pax2-cre)1Akg/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: otocyst epithelium Trace Regionally restricted 2A2-6 Expression in the cristae prosensory domain was almost completely absent compared with the control. Expression in cochlear prosensory domain was similar as in the wild-type.


Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
03/18/2025
MGI 6.24
The Jackson Laboratory