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Gene Expression Data
Assay Details
Assay
Reference: J:180770 Bjerknes M, et al., Origin of the brush cell lineage in the mouse intestinal epithelium. Dev Biol. 2012 Feb 15;362(2):194-218
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6741117
Gene symbol: Atoh1
Gene name: atonal bHLH transcription factor 1
Reporter: GFP
Direct Detection
Results
Specimen 14 Villi-1: postnatal; Atoh1tm4.1Hzo/Atoh1+ (more )
Note: Triple labeled: green - Atoh1; orange - Insm1 (assay MGI:6741065); red - Dclk1 (assay MGI:67411050).
Structure Level Pattern Image Note
TS28: intestinal villus Present 14_1-1 , 14_1-2 Expressed in mucous cells.
TS28: intestine epithelium Present 14_1-1 , 14_1-2 Expressed in mucous cells.
Specimen 14 Villi-2: postnatal; Atoh1tm4.1Hzo/Atoh1+ (more )
Note: Triple labeled: green - Atoh1; orange - Insm1 (assay MGI:6741065); red - Dclk1 (assay MGI:67411050).
Structure Level Pattern Image Note
TS28: intestinal villus Present 14_2-2 , 14_2-1 Expressed in mucous cells.
TS28: intestine epithelium Present 14_2-2 , 14_2-1 Expressed in mucous cells.
Specimen 14 Crypts-1: postnatal; Atoh1tm4.1Hzo/Atoh1+ (more )
Note: Triple labeled: green - Atoh1; orange - Insm1 (assay MGI:6741065); red - Dclk1 (assay MGI:67411050).
Structure Level Pattern Image Note
TS28: crypt of lieberkuhn Present 14_3-2 , 14_3-1 Expressed in Paneth cells. Weakly expressed in immature brush cells (Dclk1+ Insm1-) in the lower crypt.
TS28: intestine epithelium Present 14_3-2 , 14_3-1 Expressed in Paneth cells. Weakly expressed in immature brush cells (Dclk1+ Insm1-) in the lower crypt.
Specimen 14 Crypts-2: postnatal; Atoh1tm4.1Hzo/Atoh1+ (more )
Note: Triple labeled: green - Atoh1; orange - Insm1 (assay MGI:6741065); red - Dclk1 (assay MGI:67411050).
Structure Level Pattern Image Note
TS28: crypt of lieberkuhn Weak 14_4-2 , 14_4-1 Weakly expressed in immature brush cells (Dclk1+ Insm1-) and immature Insm1+ enteroendocrine cells in the lower crypt.
TS28: intestine epithelium Weak 14_4-2 , 14_4-1 Weakly expressed in immature brush cells (Dclk1+ Insm1-) and immature Insm1+ enteroendocrine cells in the lower crypt.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory