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Gene Expression Data
Assay Details
Assay
Reference: J:244562 Giese APJ, et al., CIB2 interacts with TMC1 and TMC2 and is essential for mechanotransduction in auditory hair cells. Nat Commun. 2017 Jun 29;8(1):43
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6723923
Gene symbol: Cib2
Gene name: calcium and integrin binding family member 2
Results
Specimen 1c tm1a/+: postnatal day 12; Cib2tm1a(EUCOMM)Wtsi/Cib2+ (more )
Structure Level Pattern Image Note
TS28: organ of Corti Present Regionally restricted 1c tm1a/+ CIB2 , 1c tm1a/+ (merge) In inner hair cells, expression along length of stereocilia and accumulated at tips of shortest stereocilia.
Specimen 1c tm1a/tm1a: postnatal day 12; Cib2tm1a(EUCOMM)Wtsi/Cib2tm1a(EUCOMM)Wtsi (more )
Structure Level Pattern Image Note
TS28: organ of Corti Absent 1c tm1a/tm1a (merge) , 1c tm1a/tm1a CIB2 No expression in sterocilia bundles.
Specimen 1c F91S/F91S: postnatal day 12; Cib2tm1.1Zma/Cib2tm1.1Zma (more )
Structure Level Pattern Image Note
TS28: organ of Corti Present Regionally restricted 1c F91S/F91S CIB2 , 1c F91S/F91S (merge) Authors report expression in stereocilia not affected.
Specimen 1d tm1a/+: postnatal day 12; Cib2tm1a(EUCOMM)Wtsi/Cib2+ (more )
Structure Level Pattern Image Note
TS28: organ of Corti Present Regionally restricted 1d tm1a/+ In outer hair cells, punctate expression along length of sterocilia, including at the very tips.
Specimen 1d tm1a/tm1a: postnatal day 12; Cib2tm1a(EUCOMM)Wtsi/Cib2tm1a(EUCOMM)Wtsi (more )
Structure Level Pattern Image Note
TS28: organ of Corti Absent 1d tm1a/tm1a No expression in sterocilia bundles.
Specimen 1d F91S/F91S: postnatal day 12; Cib2tm1.1Zma/Cib2tm1.1Zma (more )
Structure Level Pattern Image Note
TS28: organ of Corti Present Regionally restricted 1d F91S/F91S Authors report expression in stereocilia not affected.
Specimen 1f: postnatal day 12; Cib2tm1.1Zma/Cib2+ (more )
Structure Level Pattern Image Note
TS28: organ of Corti Present 1f Expression in sterocilia of cochlear hair cells detected as early as P5.
Specimen S2a: postnatal day 5; Cib2tm1a(EUCOMM)Wtsi/Cib2+ (more )
Structure Level Pattern Image Note
TS28: organ of Corti Present Regionally restricted S2a CIB2 Actin (right) , S2a CIB2 Actin (left) , S2a CIB2 Expression in sterocilia of cochlear hair cells detected as early as P5.
Specimen S2b Outer hair cells (row 1): postnatal day 12; Cib2tm1a(EUCOMM)Wtsi/Cib2+ (more )
Structure Level Pattern Image Note
TS28: organ of Corti Present Regionally restricted S2b Outer hair cells (row 1) Expression in sterocilia of cochlear hair cells,
Specimen S2b Outer hair cells (row 2): postnatal day 12; Cib2tm1a(EUCOMM)Wtsi/Cib2+ (more )
Structure Level Pattern Image Note
TS28: organ of Corti Present Regionally restricted S2b Outer hair cells (row 2) Expression in sterocilia of cochlear hair cells,
Specimen S2b Outer hair cells (row 3): postnatal day 12; Cib2tm1a(EUCOMM)Wtsi/Cib2+ (more )
Structure Level Pattern Image Note
TS28: organ of Corti Present Regionally restricted S2b Outer hair cells (row 3) Expression in sterocilia of cochlear hair cells,
Specimen S2b Outer hair cells (row 4): postnatal day 12; Cib2tm1a(EUCOMM)Wtsi/Cib2+ (more )
Structure Level Pattern Image Note
TS28: organ of Corti Present Regionally restricted S2b Outer hair cells (row 4) Expression in sterocilia of cochlear hair cells,
Specimen S2b Outer hair cells (row 5): postnatal day 12; Cib2tm1a(EUCOMM)Wtsi/Cib2+ (more )
Structure Level Pattern Image Note
TS28: organ of Corti Present Regionally restricted S2b Outer hair cells (row 5) Expression in sterocilia of cochlear hair cells,
Specimen S2b Outer hair cells (row 6): postnatal day 12; Cib2tm1a(EUCOMM)Wtsi/Cib2+ (more )
Structure Level Pattern Image Note
TS28: organ of Corti Present Regionally restricted S2b Outer hair cells (row 6) Expression in sterocilia of cochlear hair cells,
Specimen S2b Inner hair cells (row 1): postnatal day 12; Cib2tm1a(EUCOMM)Wtsi/Cib2+ (more )
Structure Level Pattern Image Note
TS28: organ of Corti Present Regionally restricted S2b Inner hair cells (row 1) Expression in sterocilia of cochlear hair cells,
Specimen S2b Inner hair cells (row 2): postnatal day 12; Cib2tm1a(EUCOMM)Wtsi/Cib2+ (more )
Structure Level Pattern Image Note
TS28: organ of Corti Present Regionally restricted S2b Inner hair cells (row 2) Expression in sterocilia of cochlear hair cells,
Specimen S2b Inner hair cells (row 3): postnatal day 12; Cib2tm1a(EUCOMM)Wtsi/Cib2+ (more )
Structure Level Pattern Image Note
TS28: organ of Corti Present Regionally restricted S2b Inner hair cells (row 3) Expression in sterocilia of cochlear hair cells,
Specimen S2b Inner hair cells (row 4): postnatal day 12; Cib2tm1a(EUCOMM)Wtsi/Cib2+ (more )
Structure Level Pattern Image Note
TS28: organ of Corti Present Regionally restricted S2b Inner hair cells (row 4) Expression in sterocilia of cochlear hair cells,
Specimen S2b Inner hair cells (row 5): postnatal day 12; Cib2tm1a(EUCOMM)Wtsi/Cib2+ (more )
Structure Level Pattern Image Note
TS28: organ of Corti Present Regionally restricted S2b Inner hair cells (row 5) Expression in sterocilia of cochlear hair cells,
Specimen S2b Inner hair cells (row 6): postnatal day 12; Cib2tm1a(EUCOMM)Wtsi/Cib2+ (more )
Structure Level Pattern Image Note
TS28: organ of Corti Present Regionally restricted S2b Inner hair cells (row 6) Expression in sterocilia of cochlear hair cells,
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
MGI 6.24 		The Jackson Laboratory