About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:266577 Rodrigo Albors A, et al., Lineage tracing of axial progenitors using Nkx1-2CreER(T2) mice defines their trunk and tail contributions. Development. 2018 Oct 2;145(19):dev164319
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6718555
Gene symbol: Nkx1-2
Gene name: NK1 homeobox 2
Reporter: Cre
Probe: Cre/ERT2 probe2
Probe preparation: Antisense RNA
Results
Specimen S3A: embryonic day 7.5; Nkx1-2tm2296.1(cre/ERT2)Arte/Nkx1-2+ (more )
Note: late-streak stage embryo (lateral view)
Structure Level Pattern Image Note
TS10: embryo Absent S3A
Specimen S3B: embryonic day 7.5; Nkx1-2tm2296.1(cre/ERT2)Arte/Nkx1-2+ (more )
Note: late-streak/early allantoic bud stage embryo (lateral view)
Structure Level Pattern Image Note
TS10: embryo Present Regionally restricted S3B Expression is seen in the caudal lateral epiblast.
Specimen S3C: embryonic day 7.5; Nkx1-2tm2296.1(cre/ERT2)Arte/Nkx1-2+ (more )
Note: early/late headfold stage embryo (lateral view)
Structure Level Pattern Image Note
TS11: primitive streak Present S3C Expression is seen in and alongside the primitive streak, in cells of the caudal lateral epiblast.
TS11: embryo Present Regionally restricted S3C Expression is seen in and alongside the primitive streak, in cells of the caudal lateral epiblast.
TS11: node Present S3C
Specimen S3Ca: embryonic day 7.5; Nkx1-2tm2296.1(cre/ERT2)Arte/Nkx1-2+ (more )
Note: early/late headfold stage embryo (transverse section)
Structure Level Pattern Image Note
TS11: primitive streak Present S3Ca Expression is seen in and alongside the primitive streak, in cells of the caudal lateral epiblast.
TS11: embryo Present Regionally restricted S3Ca Expression is seen in and alongside the primitive streak, in cells of the caudal lateral epiblast.
TS11: endoderm Ambiguous Single cells S3Ca Expression might be expressed in a few cells in the posterior endoderm.
Specimen S3Cb: embryonic day 7.5; Nkx1-2tm2296.1(cre/ERT2)Arte/Nkx1-2+ (more )
Note: early/late headfold stage embryo (transverse section)
Structure Level Pattern Image Note
TS11: primitive streak Present S3Cb Expression is seen in and alongside the primitive streak, in cells of the caudal lateral epiblast.
TS11: embryo Present Regionally restricted S3Cb Expression is seen in and alongside the primitive streak, in cells of the caudal lateral epiblast.
Specimen S3Cc: embryonic day 7.5; Nkx1-2tm2296.1(cre/ERT2)Arte/Nkx1-2+ (more )
Note: early/late headfold stage embryo (transverse section)
Structure Level Pattern Image Note
TS11: primitive streak Present S3Cc Expression is seen in the posterior of the embryo.
TS11: embryo Present Regionally restricted S3Cc Expression is seen in and alongside the primitive streak, in cells of the caudal lateral epiblast.
Specimen S3D: embryonic day 8.5; Nkx1-2tm2296.1(cre/ERT2)Arte/Nkx1-2+ (more )
Note: dorsal view
Structure Level Pattern Image Note
TS13: neural plate Present S3D
TS13: primitive streak Present S3D
TS13: embryo Present Regionally restricted S3D Expression is highest in epiblast cells in the node region and in the caudal lateral epiblast cells just posterior to the node.
Specimen S3Da: embryonic day 8.5; Nkx1-2tm2296.1(cre/ERT2)Arte/Nkx1-2+ (more )
Note: transverse section
Structure Level Pattern Image Note
TS13: neural plate Present S3Da
TS13: notochord Absent S3Da
Specimen S3Db: embryonic day 8.5; Nkx1-2tm2296.1(cre/ERT2)Arte/Nkx1-2+ (more )
Note: transverse section
Structure Level Pattern Image Note
TS13: neural plate Present S3Db
Specimen S3Dc: embryonic day 8.5; Nkx1-2tm2296.1(cre/ERT2)Arte/Nkx1-2+ (more )
Note: transverse section
Structure Level Pattern Image Note
TS13: primitive streak Present S3Dc
TS13: embryo Present Regionally restricted S3Dc Expression is seen in the caudal lateral epiblast cells just posterior to the node.
Specimen S3Dd: embryonic day 8.5; Nkx1-2tm2296.1(cre/ERT2)Arte/Nkx1-2+ (more )
Note: transverse section
Structure Level Pattern Image Note
TS13: embryo Absent S3Dd No expression is seen in the posterior-most section.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory