Nkx1-2tm2296.1(cre/ERT2)Arte
Targeted Allele Detail
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Symbol: |
Nkx1-2tm2296.1(cre/ERT2)Arte |
Name: |
NK1 homeobox 2; targeted mutation 2296.1, TaconicArtemis |
MGI ID: |
MGI:6718289 |
Synonyms: |
Nkx1-2CreERT2 |
Gene: |
Nkx1-2 Location: Chr7:132197968-132201366 bp, - strand Genetic Position: Chr7, 76.3 cM
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Alliance: |
Nkx1-2tm2296.1(cre/ERT2)Arte page
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Germline Transmission: |
Earliest citation of germline transmission:
J:266577
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Parent Cell Line: |
Not Specified (ES Cell)
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Strain of Origin: |
C57BL/6NTac
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Allele Type: |
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Targeted (Recombinase) |
Mutation: |
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Insertion
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Nkx1-2tm2296.1(cre/ERT2)Arte expression driven by
1 gene
Knock-in expression driven by:
Organism |
Driver Gene |
Note |
mouse |
Nkx1-2 (MGI:104806) |
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Mutation details: The targeting construct replaced the coding sequence in exon 1 with a cre/ERT2 fusion, polyadenylation sequence, and F3-flanked puromycin resistance cassette. Flp-mediated recombination removed the selection cassette.
(J:266577)
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Activity: |
Tissue activity of this recombinase allele
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Driver:
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Nkx1-2
(mouse)
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Mouse strains and cell lines
available from the International Mouse Strain Resource
(IMSR) |
Carrying this Mutation: |
Mouse Strains: 0 strains available
Cell Lines: 0 lines available
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Carrying any Nkx1-2 Mutation: |
13 strains or lines available
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Original: |
J:266577 Rodrigo Albors A, et al., Lineage tracing of axial progenitors using Nkx1-2CreER(T2) mice defines their trunk and tail contributions. Development. 2018 Oct 2;145(19):dev164319 |
All: |
5 reference(s) |
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