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Gene Expression Data
Assay Details
Assay
Reference: J:231231 Abby E, et al., Implementation of meiosis prophase I programme requires a conserved retinoid-independent stabilizer of meiotic transcripts. Nat Commun. 2016;7:10324
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6715978
Gene symbol: H2ax
Gene name: H2A.X variant histone
Results
Specimen 6b Lepto Meioc+/+: postnatal day 16 (more )
Note: Leptotene. Double labeled: red - H2ax; green - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS28: spermatocyte Present 6b Meioc+/+ Lepto Sycp3/gamma-H2ax
Specimen 6b Lepto Meioc-/-: postnatal day 16; Meioctm1a(KOMP)Wtsi/Meioctm1a(KOMP)Wtsi (more )
Note: Leptotene. Double labeled: red - H2ax; green - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS28: spermatocyte Present 6b Meioc-/- Lepto Sycp3/gamma-H2ax All spermatocytes were positive for H2ax in mutant testis.
Specimen 6b Zygo Meioc+/+: postnatal day 16 (more )
Note: Zygotene. Double labeled: red - H2ax; green - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS28: spermatocyte Present 6b Meioc+/+ Zygo Sycp3/gamma-H2ax
Specimen 6b Zygo-like Meioc-/- top: postnatal day 16; Meioctm1a(KOMP)Wtsi/Meioctm1a(KOMP)Wtsi (more )
Note: Zygotene-like. Double labeled: red - H2ax; green - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS28: spermatocyte Present 6b Meioc-/- Zygo-like Sycp3/gamma-H2ax top All spermatocytes were positive for H2ax in mutant testis.
Specimen 6b Pachy Meioc+/+: postnatal day 16 (more )
Note: Pachytene. Double labeled: red - H2ax; green - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS28: spermatocyte Present 6b Meioc+/+ Pachy Sycp3/gamma-H2ax
Specimen 6b Zygo-like Meioc-/- bottom: postnatal day 16; Meioctm1a(KOMP)Wtsi/Meioctm1a(KOMP)Wtsi (more )
Note: Zygotene-like. Double labeled: red - H2ax; green - Sycp3 (assay MGI:6695313).
Structure Level Pattern Image Note
TS28: spermatocyte Present 6b Meioc-/- Zygo-like Sycp3/gamma-H2ax bottom All spermatocytes were positive for H2ax in mutant testis.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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04/30/2024
MGI 6.23 		The Jackson Laboratory