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Gene Expression Data
Assay Details
Assay
Reference: J:294646 Stupnikov MR, et al., Jagged and Delta-like ligands control distinct events during airway progenitor cell differentiation. Elife. 2019 Oct 21;8:e50487
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6695155
Gene symbol: Fut4
Gene name: fucosyltransferase 4
Antibody: Anti-Stage-Specific Embryonic Antigen-1 Antibody, clone MC-480
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 3D control: embryonic day 18.5 (more )
Note: Double labeled: green - Fut4; red - Calca (assay MGI:6695174).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present 3D inset Expressed in secretory precursors.
Specimen 3D Jag1/2 cnull: embryonic day 18.5; Jag1tm1Jlew/Jag1tm1Jlew, Jag2tm2.1Grid/Jag2tm2.1Grid, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: green - Fut4; red - Calca (assay MGI:6695174).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present Clusters 3D left Expressed only in secretory precursors tightly associated with the developing neuroepithelial bodies. Nearly absent expression outside the neuroepithelial bodies.
Specimen 5A control: embryonic day 18.5 (more )
Note: Double labeled: green - Fut4; red - Notch1 (assay MGI:6695196).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present 5A control middle Expressed in secretory precursors.
Specimen 5A Dll1/4 cnull: embryonic day 18.5; Dll1tm1Mjo/Dll1tm1Mjo, Dll4tm1Frad/Dll4tm1Frad, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: green - Fut4; red - Notch1 (assay MGI:6695196).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present 5A cKO middle Expressed in secretory precursors, similar as in the control.
Specimen 5A control-2: embryonic day 18.5 (more )
Note: Double labeled: green - Fut4; red - Calca (assay MGI:6695174).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present 5A control lower Expressed in secretory precursors.
Specimen 5A Dll1/4 cnull-2: embryonic day 18.5; Dll1tm1Mjo/Dll1tm1Mjo, Dll4tm1Frad/Dll4tm1Frad, Shhtm1(EGFP/cre)Cjt/Shh+ (more )
Note: Conditional mutant. Double labeled: green - Fut4; red - Calca (assay MGI:6695174).
Structure Level Pattern Image Note
TS26: lobar bronchus epithelium Present 5A cKO lower Expressed in secretory precursors, similar as in the control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/07/2024
MGI 6.23 		The Jackson Laboratory