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Gene Expression Data
Assay Details
Assay
Reference: J:297547 Leca I, et al., A proteomic survey of microtubule-associated proteins in a R402H TUBA1A mutant mouse. PLoS Genet. 2020 Nov;16(11):e1009104
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6695147
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-cleaved Caspase-3 (Asp175; #9661)
Detection system: Secondary antibody coupled to Alexa Fluor 568
Assay notes: Specimens were subjected to heat-mediated antigen retrieval. The antibody used recognizes the cleaved form of the protein.
Results
Specimen 4H: embryonic day 18.5; Emx1tm1(cre)Krj/Emx1+ (more )
Note: coronal section
Structure Level Pattern Image Note
TS26: cerebral cortex Absent 4H This antibody is used to stain apoptotic cells.
Specimen 4I: embryonic day 18.5; Tuba1atm1.1Dak/Tuba1a+, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. coronal section
Structure Level Pattern Image Note
TS26: cerebral cortex Present Single cells 4I This antibody is used to stain apoptotic cells.
Specimen 4J: embryonic day 18.5; Tuba1atm1.1Dak/Tuba1atm1.1Dak, Emx1tm1(cre)Krj/Emx1+ (more )
Note: Conditional mutant. coronal section
Structure Level Pattern Image Note
TS26: cerebral cortex Present Single cells 4J' , 4J The number of apoptotic cells is significantly increased in the homozygote.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory