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Gene Expression Data
Assay Details
Assay
Reference: J:254788 Chen Z, et al., p75 Is Required for the Establishment of Postnatal Sensory Neuron Diversity by Potentiating Ret Signaling. Cell Rep. 2017 Oct 17;21(3):707-720
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6694332
Gene symbol: Ret
Gene name: ret proto-oncogene
Antibody: anti-Ret (AF482)
Detection system: Alexa Fluor 546
Assay notes: Two antibodies were described, but the one used in this assay was not detailed. Ret antibody (sc-167) MGI:6694317 may have been used in this assay.
Results
Specimen 1B/C: postnatal day 14 (more )
Note: Double labeled: red - Ret; green - p75 (Ngfr assay MGI:6694330).
Structure Level Pattern Image Note
TS28: L4 dorsal root ganglion Present 1B
Specimen 5K: postnatal day 14; Ngfrtm1.1Utsw/Ngfrtm1.1Utsw (more )
Structure Level Pattern Image Note
TS28: dorsal root ganglion Present 5K
Specimen 5L: postnatal day 14; Isl1tm1(cre)Tmj/Isl1+, Ngfrtm1.1Utsw/Ngfrtm1.1Utsw (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: dorsal root ganglion Present 5L Expression not changed.
Specimen 6J/K: postnatal adult; Ngfrtm1.1Utsw/Ngfrtm1.1Utsw (more )
Note: Double labeled: red - Ret; green - Prph (assay MGI:6694340).
Structure Level Pattern Image Note
TS28: L4 dorsal root ganglion Present 6J , 6K
Specimen 6M/N: postnatal adult; Isl1tm1(cre)Tmj/Isl1+, Ngfrtm1.1Utsw/Ngfrtm1.1Utsw (more )
Note: Conditional mutant. Double labeled: red - Ret; green - Prph (assay MGI:6694340).
Structure Level Pattern Image Note
TS28: L4 dorsal root ganglion Present 6N , 6M
Specimen S5H: postnatal day 0; Ngfrtm1.1Utsw/Ngfrtm1.1Utsw (more )
Structure Level Pattern Image Note
TS27: lumbar dorsal root ganglion Present S5H
Specimen S5I: postnatal day 0; Isl1tm1(cre)Tmj/Isl1+, Ngfrtm1.1Utsw/Ngfrtm1.1Utsw (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS27: lumbar dorsal root ganglion Present S5I No gross difference in expression compared with control.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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05/21/2024
MGI 6.23 		The Jackson Laboratory