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Gene Expression Data
Assay Details
Assay
Reference: J:254788 Chen Z, et al., p75 Is Required for the Establishment of Postnatal Sensory Neuron Diversity by Potentiating Ret Signaling. Cell Rep. 2017 Oct 17;21(3):707-720
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6694331
Gene symbol: Ngfr
Gene name: nerve growth factor receptor (TNFR superfamily, member 16)
Antibody: anti-p75
Detection system: Alexa Fluor 546
Results
Specimen 5A: embryonic day 10.5; Ngfrtm1.1Utsw/Ngfrtm1.1Utsw (more )
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present 5A
Specimen 5B: embryonic day 10.5; Isl1tm1(cre)Tmj/Isl1+, Ngfrtm1.1Utsw/Ngfrtm1.1Utsw (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: dorsal root ganglion Present 5B Expression not reduced.
Specimen 5C: embryonic day 12.5; Ngfrtm1.1Utsw/Ngfrtm1.1Utsw (more )
Structure Level Pattern Image Note
TS20: dorsal root ganglion Present 5C
Specimen 5D: embryonic day 12.5; Isl1tm1(cre)Tmj/Isl1+, Ngfrtm1.1Utsw/Ngfrtm1.1Utsw (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS20: dorsal root ganglion Trace 5D Expression markedly reduced.
Specimen 5E: postnatal adult; Ngfrtm1.1Utsw/Ngfrtm1.1Utsw (more )
Structure Level Pattern Image Note
TS28: dorsal root ganglion Present 5E
Specimen 5F: postnatal adult; Isl1tm1(cre)Tmj/Isl1+, Ngfrtm1.1Utsw/Ngfrtm1.1Utsw (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS28: dorsal root ganglion Weak Regionally restricted 5F Expression markedly reduced, predominantly in satellite cells.
Specimen S6B/C: postnatal adult; Ngfrtm1.1Utsw/Ngfrtm1.1Utsw (more )
Note: Double labeled: red - Ngfr; green - CGRP (Calca assay MGI:6694337).
Structure Level Pattern Image Note
TS28: L4 dorsal root ganglion Present S6C , S6B
Specimen S6E/F: postnatal adult; Isl1tm1(cre)Tmj/Isl1+, Ngfrtm1.1Utsw/Ngfrtm1.1Utsw (more )
Note: Conditional mutant. Double labeled: red - Ngfr; green - CGRP (Calca assay MGI:6694337).
Structure Level Pattern Image Note
TS28: L4 dorsal root ganglion Trace Regionally restricted S6F , S6E Expression effectively removed from majority of CGRP (Calca)-expressing neurons.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory