Gene Expression Data
Assay Details
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Assay
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Reference:
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J:184934
Lee SH, et al., Runx2 protein stabilizes hypoxia-inducible factor-1alpha through competition with von Hippel-Lindau protein (pVHL) and stimulates angiogenesis in growth plate hypertrophic chondrocytes. J Biol Chem. 2012 Apr 27;287(18):14760-71
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6690658
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Gene symbol:
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Pecam1
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Gene name:
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platelet/endothelial cell adhesion molecule 1
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Antibody:
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Anti-CD31
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
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Results
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Specimen
7C WT:
embryonic day 15.5
(more  )
Specimen
7C WT:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: tibia |
Present |
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7C WT CD31
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Expression was detected in the hypertrophic zone.
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Specimen
7C Runx2+/-:
embryonic day 15.5; Runx2tm1Mjo/Runx2 +
(more )
Specimen
7C Runx2+/-:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Runx2tm1Mjo/Runx2+
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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Specimen
7C Runx2-/-:
(close )
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Genetic Background:
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Not Specified
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Mutant Allele(s):
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Runx2tm1Mjo/Runx2tm1Mjo
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Age:
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embryonic day 15.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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4% Paraformaldehyde
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS23: tibia |
Weak |
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7C Runx2-/- CD31
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Expression was detected in the hypertrophic zone. Vascular density was decreased in the mutant.
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Analysis Tools
