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Gene Expression Data
Assay Details
Assay
Reference: J:186516 Baron O, et al., Cooperation of nuclear fibroblast growth factor receptor 1 and Nurr1 offers new interactive mechanism in postmitotic development of mesencephalic dopaminergic neurons. J Biol Chem. 2012 Jun 8;287(24):19827-40
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6681923
Gene symbol: Th
Gene name: tyrosine hydroxylase
Antibody: anti-TH (T1299)
Detection system: Secondary antibody coupled to Alexa Fluor 568
Results
Specimen 1B/D: embryonic day 14.5 (more )
Note: Ventral midbrain. Double labeled: red - Th; green - Nr4a2 (assay MGI:6681921).
Structure Level Pattern Image Note
TS22: midbrain mantle layer Present 1D , 1B
Specimen 1F/G/H: embryonic day 14.5; Fgf2tm1Zllr/Fgf2tm1Zllr (more )
Note: Ventral midbrain. Double labeled: red - Th; green - Nr4a2 (assay MGI:6681921).
Structure Level Pattern Image Note
TS22: midbrain mantle layer Present 1F , 1G , 1H Similar as in the wild-type.
Specimen 1J/L: embryonic day 14.5 (more )
Note: Ventral midbrain. Double labeled: red - Th; green - Fgfr1 (assay MGI:6681924).
Structure Level Pattern Image Note
TS22: midbrain mantle layer Present 1J , 1L
Specimen 1N/P: embryonic day 14.5; Fgf2tm1Zllr/Fgf2tm1Zllr (more )
Note: Ventral midbrain. Double labeled: red - Th; green - Fgfr1 (assay MGI:6681924).
Structure Level Pattern Image Note
TS22: midbrain mantle layer Present 1N , 1P Similar as in the wild-type.
Specimen 2a': embryonic day 14.5 (more )
Note: Ventral midbrain. Double labeled: red - Th; green - Fgfr1 (assay MGI:6681924).
Structure Level Pattern Image Note
TS22: brain subventricular zone Absent 2a' right
Specimen 2a": embryonic day 14.5 (more )
Note: Ventral midbrain. Double labeled: red - Th; green - Fgfr1 (assay MGI:6681924).
Structure Level Pattern Image Note
TS22: midbrain mantle layer Present 2a" right
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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