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Gene Expression Data
Assay Details
Assay
Reference: J:186516 Baron O, et al., Cooperation of nuclear fibroblast growth factor receptor 1 and Nurr1 offers new interactive mechanism in postmitotic development of mesencephalic dopaminergic neurons. J Biol Chem. 2012 Jun 8;287(24):19827-40
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6681924
Gene symbol: Fgfr1
Gene name: fibroblast growth factor receptor 1
Antibody: Anti-Fgfr1
Detection system: Secondary antibody coupled to Alexa Fluor 488
Results
Specimen 1I/J/K/L: embryonic day 14.5 (more )
Note: Ventral midbrain. Double labeled: green - Fgfr1; red - Th (assay MGI:6681923).
Structure Level Pattern Image Note
TS22: midbrain Present Widespread 1J , 1L , 1I , 1K
Specimen 1M/N/O/P: embryonic day 14.5; Fgf2tm1Zllr/Fgf2tm1Zllr (more )
Note: Ventral midbrain. Double labeled: green - Fgfr1; red - Th (assay MGI:6681923).
Structure Level Pattern Image Note
TS22: midbrain Present Widespread 1P , 1O , 1N , 1M Similar as in the wild-type.
Specimen 2a': embryonic day 14.5 (more )
Note: Ventral midbrain. Double labeled: green - Fgfr1; red - Th (assay MGI:6681923).
Structure Level Pattern Image Note
TS22: brain subventricular zone Present 2a' right , 2a' middle , 2a' left A nearly uniform distribution in the cytoplasm and nucleus.
Specimen 2a": embryonic day 14.5 (more )
Note: Ventral midbrain. Double labeled: green - Fgfr1; red - Th (assay MGI:6681923).
Structure Level Pattern Image Note
TS22: midbrain mantle layer Present 2a" middle , 2a" right , 2a" left A prominent accumulation in the nuclear proportion of the differentiated neurons expressing Th.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory