Fgf8 RNA in situ Gene Expression Assay

Gene Expression Data
Assay Details

Assay

Reference:	J:290019 Jin YR, et al., Canonical WNT/beta-Catenin Signaling Activated by WNT9b and RSPO2 Cooperation Regulates Facial Morphogenesis in Mice. Front Cell Dev Biol. 2020;8:264
Assay type:	RNA in situ
MGI Accession ID:	MGI:6514117
Gene symbol:	Fgf8
Gene name:	fibroblast growth factor 8

Probe:

Fgf8 probe115

Results

3A Fgf8 wt ©

Specimen 3A wt: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: 1st branchial arch ectoderm	Present		3A Fgf8 wt
TS17: nasal process ectoderm	Present		3A Fgf8 wt

Specimen 3A Wnt9b-/-: embryonic day 10.5; Wnt9b^tm1.1Amc/Wnt9b^tm1.1Amc (more

)

Structure	Level	Pattern	Image	Note
TS17: 1st branchial arch ectoderm	Present		3A Fgf8 Wnt9b-/-
TS17: nasal process ectoderm	Present		3A Fgf8 Wnt9b-/-

Specimen 3A Rspo2-/-: embryonic day 10.5; Rspo2^tm1.1Jky/Rspo2^tm1.1Jky (more

)

Structure	Level	Pattern	Image	Note
TS17: 1st branchial arch ectoderm	Present		3A Fgf8 Rspo2-/-
TS17: nasal process ectoderm	Present		3A Fgf8 Rspo2-/-

Specimen 3A Wnt9b-/-;Rspo2-/-: embryonic day 10.5; Rspo2^tm1.1Jky/Rspo2^tm1.1Jky, Wnt9b^tm1.1Amc/Wnt9b^tm1.1Amc (more

)

Structure	Level	Pattern	Image	Note
TS17: 1st branchial arch ectoderm	Weak		3A Fgf8 Wnt9b-/-;Rspo2-/-	Expression was dramatically reduced in the double knockout.
TS17: nasal process ectoderm	Weak		3A Fgf8 Wnt9b-/-;Rspo2-/-	Expression was dramatically reduced in the double knockout.

7B Fgf8 wt ©

Specimen 7B wt: embryonic day 10.5 (more

)

Structure	Level	Pattern	Image	Note
TS17: 1st branchial arch ectoderm	Present		7B Fgf8 wt
TS17: nasal process ectoderm	Present		7B Fgf8 wt

Specimen 7B Lgr4-/-: embryonic day 10.5; Lgr4^tm1.2Knis/Lgr4^tm1.2Knis (more

)

Structure	Level	Pattern	Image	Note
TS17: 1st branchial arch ectoderm	Present		7B Fgf8 Lgr4-/-	Expression was primarily unaffected within the facial process of the mutant.
TS17: nasal process ectoderm	Present		7B Fgf8 Lgr4-/-	Expression was primarily unaffected within the facial process of the mutant.

Specimen 7B Lgr5-/-: embryonic day 10.5; Lgr5^{tm1(cre/ERT2)Cle}/Lgr5^{tm1(cre/ERT2)Cle} (more

)

Structure	Level	Pattern	Image	Note
TS17: 1st branchial arch ectoderm	Present		7B Fgf8 Lgr5-/-	Expression was primarily unaffected within the facial process of the mutant.
TS17: nasal process ectoderm	Present		7B Fgf8 Lgr5-/-	Expression was primarily unaffected within the facial process of the mutant.

Specimen 7B Lgr6-/-: embryonic day 10.5; Lgr6^{tm2.1(cre/ERT2)Cle}/Lgr6^{tm2.1(cre/ERT2)Cle} (more

)

Structure	Level	Pattern	Image	Note
TS17: 1st branchial arch ectoderm	Present		7B Fgf8 Lgr6-/-	Expression was primarily unaffected within the facial process of the mutant.
TS17: nasal process ectoderm	Present		7B Fgf8 Lgr6-/-	Expression was primarily unaffected within the facial process of the mutant.

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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