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Gene Expression Data
Assay Details
Assay
Reference: J:280280 Rutledge EA, et al., Morphogenesis of the kidney and lung requires branch-tip directed activity of the Adamts18 metalloprotease. Dev Biol. 2019 Oct 15;454(2):156-169
Assay type: RNA in situ
MGI Accession ID: MGI:6512005
Gene symbol: Adamts18
Gene name: ADAM metallopeptidase with thrombospondin type 1 motif 18
Probe: Mm-Adamts18 (452251)
Probe preparation: Antisense
Visualized with: Chromogenic
Assay notes: RNAscope assay
Results
Specimen 1A/B: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: ureteric tip Present 1B , 1A
Specimen 1K: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: ureteric tip Present 1K
Specimen 1F/G: embryonic day 11.5 (more )
Structure Level Pattern Image Note
TS19: lung epithelium Present Regionally restricted 1F , 1G Expression is seen in the distal epithelial tips throughout branching morphogenesis.
Specimen not shown: embryonic day 18.5 (more )
Structure Level Pattern Image Note
TS26: lung Absent Expression terminates with the cessation of branching growth.
Specimen 1L: postnatal day 0 (more )
Structure Level Pattern Image Note
TS27: ureteric tip Present 1L Expression is markedly downregulated from levels seen earlier in development.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
MGI 6.24 		The Jackson Laboratory