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Gene Expression Data
Assay Details
Assay
Reference: J:291094 Sheikh BN, et al., Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature. Nat Cell Biol. 2020 Jul;22(7):828-841
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6511317
Gene symbol: Pdgfrb
Gene name: platelet derived growth factor receptor, beta polypeptide
Antibody: Anti-Pdgfrb (AF1042)
Detection system: Alexa Fluor 555
Assay notes: Embedded in 6.3% (wt/vol) gelatine and 27% (wt/vol) albumin.
Results
Specimen S6e Nes-Cre T/+: embryonic day 14.5; Tg(Nes-cre)1Kln/0 (more )
Note: Double labeled: green - Pdgfrb; red - Pecam1 (assay MGI:6511316).
Structure Level Pattern Image Note
TS22: brain vascular element Present S6e Nes-Cre T/+
Specimen S6e Mof nKO: embryonic day 14.5; Kat8tm1.2Avo/Kat8tm1.2Avo, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant. Double labeled: green - Pdgfrb; red - Pecam1 (assay MGI:6511316).
Structure Level Pattern Image Note
TS22: brain vascular element Present S6e Mof nKO Authors report that recruitment of mural cells did not differ from controls.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/25/2025
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