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Gene Expression Data
Assay Details
Assay
Reference: J:291094 Sheikh BN, et al., Neural metabolic imbalance induced by MOF dysfunction triggers pericyte activation and breakdown of vasculature. Nat Cell Biol. 2020 Jul;22(7):828-841
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6511311
Gene symbol: Casp3
Gene name: caspase 3
Antibody: anti-active caspase-3 (G748A)
Detection system: Alexa Fluor 488
Results
Specimen S2b Nes-Cre T/+: embryonic day 14.5; Tg(Nes-cre)1Kln/0 (more )
Structure Level Pattern Image Note
TS22: brain Absent S2b Nes-Cre T/+
Specimen S2b Mof nKO: embryonic day 14.5; Kat8tm1.2Avo/Kat8tm1.2Avo, Tg(Nes-cre)1Kln/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: ganglionic eminence Strong S2b Mof nKO Authors report extensive cell death in ganglionic eminence region.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/24/2026
MGI 6.24 		The Jackson Laboratory