About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:297161 Javali A, et al., Modulation of beta-catenin levels regulates cranial neural crest patterning and dispersal into first pharyngeal arch. Dev Dyn. 2020 May 19;
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6505463
Gene symbol: Ctnnb1
Gene name: catenin beta 1
Results
Specimen 3He: embryonic day 9.5; E2f1Tg(Wnt1-cre)2Sor/0, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: trigeminal preganglion Strong 3He High levels of expression in proximal region (trigeminal ganglion anlage).
Specimen 3Hf: embryonic day 9.5; E2f1Tg(Wnt1-cre)2Sor/0, Gt(ROSA)26Sortm14(CAG-tdTomato)Hze/Gt(ROSA)26Sor+ (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: 1st branchial arch mesenchyme derived from neural crest Weak Regionally restricted 3Hf Reduced expression in distal region (skeletogenic cells) in first pharyngeal arch.
Specimen 4A 4SS: embryonic day 8.0 (more )
Note: 4 somites. Double labeled: red - Ctnnb1; white - Tfap2a (assay MGI:6505461).
Structure Level Pattern Image Note
TS12: migrating neural crest Present Uniform 4A 4SS Uniform levels of membrane expression in entire pool of delaminated cranial neural crest cells (CNCC).
Specimen 4Aa: embryonic day 8.0 (more )
Note: 4 somites. Double labeled: red - Ctnnb1; white - Tfap2a (assay MGI:6505461).
Structure Level Pattern Image Note
TS12: migrating neural crest Present Uniform 4Aa (right) , 4Aa (center) Uniform levels of membrane expression in entire pool of delaminated cranial neural crest cells (CNCC).
Specimen 4A 8SS: embryonic day 8.5 (more )
Note: 8 somites. Double labeled: red - Ctnnb1; white - Tfap2a (assay MGI:6505461).
Structure Level Pattern Image Note
TS13: migrating neural crest Weak Regionally restricted 4A 8SS Decreased levels of expression in distally migrated cranial neural crest cells (CNCC).
Specimen 4Ab: embryonic day 8.5 (more )
Note: 8 somites. Double labeled: red - Ctnnb1; white - Tfap2a (assay MGI:6505461).
Structure Level Pattern Image Note
TS13: migrating neural crest Weak Regionally restricted 4Ab (center) , 4Ab (right) Decreased levels of expression in distally migrated cranial neural crest cells (CNCC).
Specimen 4Ac: embryonic day 8.5 (more )
Note: 8 somites. Double labeled: red - Ctnnb1; white - Tfap2a (assay MGI:6505461).
Structure Level Pattern Image Note
TS13: migrating neural crest Weak Regionally restricted 4Ac (right) , 4Ac (center) Decreased levels of expression in distally migrated cranial neural crest cells (CNCC).
Specimen 7B beta-catenin: embryonic day 9.5; Ctnnb1tm1Mmt/Ctnnb1+, E2f1Tg(Wnt1-cre)2Sor/0 (more )
Note: Conditional mutant. Double labeled: red - Ctnnb1; green - Twist1 (assay MGI:6505464).
Structure Level Pattern Image Note
TS15: 1st branchial arch mesenchyme derived from neural crest Strong 7B (left) High levels of expression in hypoplastic pharyngeal arch.
Specimen 7B beta-catenin inset: embryonic day 9.5; Ctnnb1tm1Mmt/Ctnnb1+, E2f1Tg(Wnt1-cre)2Sor/0 (more )
Note: Conditional mutant. Double labeled: red - Ctnnb1; green - Twist1 (assay MGI:6505464).
Structure Level Pattern Image Note
TS15: 1st branchial arch mesenchyme derived from neural crest Strong Regionally restricted 7B (center right) , 7B (right) High levels of expression in Twist1-expressing cells in hypoplastic pharyngeal arch.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory