About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:160146 Rowan S, et al., Precise temporal control of the eye regulatory gene Pax6 via enhancer-binding site affinity. Genes Dev. 2010 May 15;24(10):980-5
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6502092
Gene symbol: Pknox1
Gene name: Pbx/knotted 1 homeobox
Antibody: anti-Prep1
Detection system: Cy3
Results
Specimen S1 Prep1+/+ Prep1: embryonic day 9.5 (more )
Note: Double labeled: red - Prep1 (Pknox1); green - Pax6 (assay MGI:6502091).
Structure Level Pattern Image Note
TS15: eye Present Ubiquitous S1_Prep1+/+ Prep1/Pax6 , S1_Prep1+/+ Prep1/DAPI Ubiquitous expressin in eye region and largely, but not exclusively, nuclear.
Specimen S1 Prep1i/- Prep1: embryonic day 9.5; Pknox1Gt(OST71835)Lex/Pknox1tm1Ngc (more )
Note: Double labeled: red - Prep1 (Pknox1); green - Pax6 (assay MGI:6502091).
Structure Level Pattern Image Note
TS15: eye Absent S1_Prep1i/- Prep1/DAPI , S1_Prep1i/- Prep1/Pax6 Expression largely undetectable.
Specimen S2 Pax6+/+ Prep1: embryonic day 9.25 (more )
Note: 16 somites
Structure Level Pattern Image Note
TS14: eye Present Regionally restricted S2_Pax6+/+ Prep1 Expression was both nuclear and cytoplasmic.
Specimen S2 Sey-Neu Prep1: embryonic day 9.25; Pax6Sey-Neu/Pax6Sey-Neu (more )
Note: 16 somites
Structure Level Pattern Image Note
TS14: eye Present Regionally restricted S2_Pax6Sey-Neu Prep1 Authors report expression does not depend on Pax6 expression.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/18/2025
MGI 6.24 		The Jackson Laboratory