Gene Expression Data
Assay Details
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Assay
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Reference:
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J:84975
Bach A, et al., Msx1 is required for dorsal diencephalon patterning. Development. 2003 Sep;130(17):4025-36
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Assay type:
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RNA in situ
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MGI Accession ID:
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MGI:6489889
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Gene symbol:
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Pax6
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Gene name:
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paired box 6
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Probe:
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Pax6 cDNA28
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Probe preparation:
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Antisense labelled with digoxigenin RNA
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Visualized with:
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Alkaline phosphatase
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Results
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Specimen
3E:
embryonic day 12.5
(more  )
Note: wild type; transverse section
Specimen
3E:
(close  )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Note:
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wild type; transverse section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: diencephalon |
Present |
Regionally restricted |
3E
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Expression is seen in two lateral domains adjacent to the midline; it is excluded from the midline.
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Specimen
3F:
(close )
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Genetic Background:
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B6.129P2-Msx1tm1Bero
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Mutant Allele(s):
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Msx1tm1Bero/Msx1tm1Bero
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Age:
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embryonic day 12.5
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Sex:
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Not Specified
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Type:
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section
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Note:
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transverse section
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| Structure |
Level |
Pattern |
Image |
Note |
| TS20: diencephalon |
Present |
Widespread |
3F
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In the mutant the expression domain extends over the midline, a region from which it is normally excluded.
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Specimen
5C:
embryonic day 14.5
(more )
Note: wild type; dorsal view
Specimen
5C:
(close )
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Genetic Background:
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Not Specified
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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wild type; dorsal view
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: prosomere 1 |
Present |
Regionally restricted |
5C
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Expression is excluded from the midline.
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Specimen
5D:
(close )
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Genetic Background:
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B6.129P2-Msx1tm1Bero
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Mutant Allele(s):
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Msx1tm1Bero/Msx1tm1Bero
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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Note:
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dorsal view
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: prosomere 1 |
Present |
Regionally restricted |
5D
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In the mutant expression is reduced in the dorsolateral domain, although when present, the expression domain does extend over the midline, a region from which it is normally excluded.
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Specimen
not shown:
(close )
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Genetic Background:
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B6.129P2-Msx1tm1Bero
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Mutant Allele(s):
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Msx1tm1Bero/Msx1tm1Bero
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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whole mount
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: telencephalon |
Present |
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Expression is maintained in the epiphysis and telecephalon of the mutant.
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Analysis Tools
