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Gene Expression Data
Assay Details
Assay
Reference: J:88686 Wellik DM, et al., Hox11 paralogous genes are essential for metanephric kidney induction. Genes Dev. 2002 Jun 1;16(11):1423-32
Assay type: Immunohistochemistry
MGI Accession ID: MGI:6488190
Gene symbol: Pax2
Gene name: paired box 2
Antibody: anti-Pax2
Results
Specimen 4A: embryonic day 11.5; Hoxd11tm1Mrc/Hoxd11+ (more )
Note: Double labeled: red - Pax2; green - TUNEL.
Structure Level Pattern Image Note
TS19: nephric duct Present 4A Expression in Wolffian duct.
TS19: peripheral blastema Present 4A Expression in condensed blastemal mesenchyme.
Specimen 4B: embryonic day 11.5; Hoxa11tm1Mrc/Hoxa11tm1Mrc, Hoxc11tm1Mrc/Hoxc11tm1Mrc, Hoxd11tm1Mrc/Hoxd11tm1Mrc (more )
Note: Double labeled: red - Pax2; green - TUNEL.
Structure Level Pattern Image Note
TS19: nephric duct Present 4B Expression in Wolffian duct.
TS19: metanephric mesenchyme Weak Regionally restricted 4B Authors report absence of metanephric induction.
Specimen 5C: embryonic day 10.5; Hoxc11tm1Mrc/Hoxc11+, Hoxd11tm1Mrc/Hoxd11+ (more )
Structure Level Pattern Image Note
TS17: metanephric mesenchyme Present Regionally restricted 5C Expression in metanephric blastema.
TS17: nephric duct Present 5C Expression in Wolffian duct.
Specimen 5D: embryonic day 10.5; Hoxa11tm1Mrc/Hoxa11tm1Mrc, Hoxc11tm1Mrc/Hoxc11tm1Mrc, Hoxd11tm1Mrc/Hoxd11tm1Mrc (more )
Structure Level Pattern Image Note
TS17: metanephric mesenchyme Present Regionally restricted 5D Authors report normal expression in triple mutant.
TS17: nephric duct Present 5D Expression in Wolffian duct.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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03/18/2025
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