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Hoxa11tm1Mrc
Targeted Allele Detail
Summary
Symbol: Hoxa11tm1Mrc
Name: homeobox A11; targeted mutation 1, Mario R Capecchi
MGI ID: MGI:2389126
Synonyms: Hoxd11neo
Gene: Hoxa11  Location: Chr6:52219086-52222784 bp, - strand  Genetic Position: Chr6, 25.4 cM
Alliance: Hoxa11tm1Mrc page
Mutation
origin
Germline Transmission:  Earliest citation of germline transmission: J:78766
Parent Cell Line:  Not Specified (ES Cell)
Strain of Origin:  Not Specified
Mutation
description
Allele Type:    Targeted (Null/knockout)
Mutation:    Insertion
    A neomycin selection cassette was inserted in an Eco47III site in the 5' end of the homeobox. (J:78766)
Phenotypes
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View phenotypes and curated references for all genotypes (concatenated display).
Expression
In Mice Carrying this Mutation: 15 assay results
In Structures Affected by this Mutation: 4 anatomical structure(s)
Find Mice (IMSR)
Mouse strains and cell lines available from the International Mouse Strain Resource (IMSR)
Carrying this Mutation:  Mouse Strains: 0 strains available      Cell Lines: 0 lines available
Carrying any Hoxa11 Mutation:  11 strains or lines available
References
Original:  J:78766 Boulet AM, et al., Duplication of the Hoxd11 gene causes alterations in the axial and appendicular skeleton of the mouse. Dev Biol. 2002 Sep 1;249(1):96-107
All:  7 reference(s)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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last database update
04/16/2024
MGI 6.23
The Jackson Laboratory