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Gene Expression Data
Assay Details
Assay
Reference: J:294964 Vincentz JW, et al., Variation in a Left Ventricle-Specific Hand1 Enhancer Impairs GATA Transcription Factor Binding and Disrupts Conduction System Development and Function. Circ Res. 2019 Aug 30;125(6):575-589
Assay type: RNA in situ
MGI Accession ID: MGI:6478005
Gene symbol: Hand1
Gene name: heart and neural crest derivatives expressed 1
Probe: Hand1 probe5
Probe preparation: Antisense labelled with digoxigenin RNA
Results
Specimen 2B: embryonic day 10.5; Rr132em1Abfi/Rr132+ (more )
Structure Level Pattern Image Note
TS17: primitive ventricle Present 2B Expression is seen in the left ventricle.
TS17: outflow tract Present 2B
TS17: trunk mesenchyme Present 2B Expression is seen in the lateral mesoderm.
Specimen 2C: embryonic day 10.5; Rr132em1Abfi/Rr132em1Abfi (more )
Structure Level Pattern Image Note
TS17: primitive ventricle Ambiguous 2C Expression is markedly reduced in the mutant.
TS17: outflow tract Present 2C Expression is unaffected in the mutant.
TS17: trunk mesenchyme Present 2C Expression is seen in the lateral mesoderm; it is unaffected in the mutant.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory