Gene Expression Data
Assay Details
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Assay
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Reference:
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J:261042
Welcker D, et al., AATF suppresses apoptosis, promotes proliferation and is critical for Kras-driven lung cancer. Oncogene. 2018 Mar;37(11):1503-1518
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Assay type:
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Immunohistochemistry
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MGI Accession ID:
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MGI:6477298
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Gene symbol:
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Mki67
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Gene name:
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antigen identified by monoclonal antibody Ki 67
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Antibody:
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Anti-Ki67 (SP6; ab16667)
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Detection system:
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Biotinylated secondary antibody/[Strept]avidin coupled to horseradish peroxidase
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Results
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Specimen
1d E16.5 Skin:
embryonic day 16.5
(more  )
Specimen
1d E16.5 Skin:
(close  )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: skin |
Present |
Regionally restricted |
1d Skin Ki67
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Proliferating cells were noted juxtaposed to the basal membrane.
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Specimen
1d E16.5 Liver:
embryonic day 16.5
(more )
Specimen
1d E16.5 Liver:
(close )
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Genetic Background:
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C57BL/6
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: liver |
Present |
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1d Liver Ki67
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Specimen
1e Adult Bone marrow:
postnatal adult
(more )
Specimen
1e Adult Bone marrow:
(close )
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Genetic Background:
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C57BL/6
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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Specimen
1e Adult Small intestine:
postnatal adult
(more )
Specimen
1e Adult Small intestine:
(close )
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Genetic Background:
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C57BL/6
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: small intestine |
Strong |
Regionally restricted |
1e Small intestine Ki67
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The proliferative compartment in the small intestine, confined to the bottom of the crypts, was stained strongly.
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Specimen
S1:
postnatal adult
(more )
Specimen
S1:
(close )
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Genetic Background:
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C57BL/6
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Age:
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postnatal adult
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS28: heart |
Ambiguous |
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S1_Heart Ki67
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Heart acted as a post-mitotic control.
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Specimen
2e K14;Aatf:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6 * DBA/2
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Mutant Allele(s):
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Aatftm1.1Rein/Aatftm1.1Rein
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: skin |
Present |
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2e Ki67 K14Cre-neg;Aatffl/fl
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Specimen
2e K14;Aatf:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6 * DBA/2
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Mutant Allele(s):
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Aatftm1.1Rein/Aatftm1.1Rein
Tg(KRT14-cre)1Cgn/0
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Age:
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embryonic day 14.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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Note:
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Conditional mutant.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS22: skin |
Trace |
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2e Ki67 K14Cre;Aatffl/fl
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Proliferating cells were almost entirely absent in the conditional mutant.
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Specimen
S2c K14;Aatf E16.5:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6 * DBA/2
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Mutant Allele(s):
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Aatftm1.1Rein/Aatftm1.1Rein
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: skin |
Present |
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S2c Ki67 E16.5 K14Cre-neg;Aatffl/fl
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Specimen
S2c K14;Aatf E16.5:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6 * DBA/2
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Mutant Allele(s):
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Aatftm1.1Rein/Aatftm1.1Rein
Tg(KRT14-cre)1Cgn/0
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Age:
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embryonic day 16.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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Note:
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Conditional mutant.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS24: skin |
Trace |
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S2c Ki67 E16.5 K14Cre;Aatffl/fl
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Proliferating cells were almost entirely absent in the conditional mutant.
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Specimen
S2c K14;Aatf E18.5:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6 * DBA/2
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Mutant Allele(s):
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Aatftm1.1Rein/Aatftm1.1Rein
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: skin |
Present |
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S2c Ki67 E18.5 K14Cre-neg;Aatffl/fl
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Specimen
S2c K14;Aatf E18.5:
(close )
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Genetic Background:
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involves: 129S1/Sv * C57BL/6 * DBA/2
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Mutant Allele(s):
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Aatftm1.1Rein/Aatftm1.1Rein
Tg(KRT14-cre)1Cgn/0
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Age:
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embryonic day 18.5
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Sex:
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Not Specified
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Type:
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section
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Fixation:
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Formalin
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Embedding:
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Paraffin
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Note:
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Conditional mutant.
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| Structure |
Level |
Pattern |
Image |
Note |
| TS26: skin |
Trace |
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S2c Ki67 E18.5 K14Cre;Aatffl/fl
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Proliferating cells were almost entirely absent in the conditional mutant.
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Analysis Tools