About   Help   FAQ
Gene Expression Data
Assay Details
Assay
Reference: J:104938 Pedersen A, et al., Lim 1 is required for nephric duct extension and ureteric bud morphogenesis. Dev Biol. 2005 Dec 15;288(2):571-81
Assay type: In situ reporter (knock in)
MGI Accession ID: MGI:6474086
Gene symbol: Lhx1
Gene name: LIM homeobox protein 1
Reporter: lacZ
Direct Detection
Results
Specimen 3A: embryonic day 14.5; Lhx1tm1Tmj/Lhx1+ (more )
Structure Level Pattern Image Note
TS22: metanephros Present Regionally restricted 3A Expression in developing renal vesicles.
Specimen 3B: embryonic day 14.5; Lhx1tm1Tmj/Lhx1tm2.1Bhr, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: metanephros Weak Regionally restricted 3B Expression in hypoplastic right kidney. Left kidney is absent.
Specimen 3C: embryonic day 14.5; Lhx1tm1Tmj/Lhx1+ (more )
Structure Level Pattern Image Note
TS22: nephric duct Present 3C Expression in nephric duct and Mullerian duct.
TS22: paramesonephric duct Present 3C Expression in nephric duct and Mullerian duct.
Specimen 3D: embryonic day 14.5; Lhx1tm1Tmj/Lhx1tm2.1Bhr, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS22: nephric duct Absent 3D Expression largely absent in presumptive nephric duct region.
TS22: paramesonephric duct Present Regionally restricted 3D Only most rostral portion of Mullerian duct has formed.
Specimen 6A: embryonic day 9.5; Lhx1tm1Tmj/Lhx1+ (more )
Structure Level Pattern Image Note
TS15: nephric duct Present Regionally restricted 6A Expression in nephric duct extending caudally to presumptive cloaca region.
Specimen 6B: embryonic day 9.5; Lhx1tm1Tmj/Lhx1tm2.1Bhr, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS15: nephric duct Weak Regionally restricted 6B Reduced expression in nephric duct which does not reach cloaca region.
Specimen 6C: embryonic day 10.5; Lhx1tm1Tmj/Lhx1+ (more )
Structure Level Pattern Image Note
TS17: nephric duct Present Regionally restricted 6C Expression in nephric duct which approaches wall of urogenital sinus.
Specimen 6D: embryonic day 10.5; Lhx1tm1Tmj/Lhx1tm2.1Bhr, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS17: nephric duct Weak Regionally restricted 6D Reduced expression in nephric duct which extends less caudally and does not reach wall of urogenital sinus.
Specimen 6E: embryonic day 10.75; Lhx1tm1Tmj/Lhx1+ (more )
Structure Level Pattern Image Note
TS18: ureteric bud Present 6E Ureteric bud grows out into mesenchyme.
TS18: nephric duct Present Regionally restricted 6E Terminal portion of nephric duct is present.
Specimen 6F: embryonic day 10.75; Lhx1tm1Tmj/Lhx1tm2.1Bhr, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS18: ureteric bud Weak Regionally restricted 6F Ureteric bud is smaller.
TS18: nephric duct Absent 6F Terminal portion of nephric duct is not apparent.
Specimen 6G: embryonic day 11.5; Lhx1tm1Tmj/Lhx1+ (more )
Structure Level Pattern Image Note
TS19: ureteric bud Present Regionally restricted 6G Ureteric bud forms a T-shaped structure.
Specimen 6H: embryonic day 11.5; Lhx1tm1Tmj/Lhx1tm2.1Bhr, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: ureteric bud Weak Regionally restricted 6H Ureteric bud is smaller and expression is reduced.
Specimen 6I: embryonic day 11.5; Lhx1tm1Tmj/Lhx1+ (more )
Structure Level Pattern Image Note
TS19: ureteric bud Present 6I
Specimen 6J: embryonic day 11.5; Lhx1tm1Tmj/Lhx1tm2.1Bhr, Tg(Pax2-cre)10Shwl/0 (more )
Note: Conditional mutant.
Structure Level Pattern Image Note
TS19: ureteric bud Weak Regionally restricted 6J Y-shaped ureteric bud.
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
Send questions and comments to User Support. 		last database update
03/25/2025
MGI 6.24 		The Jackson Laboratory